长春中医药大学学报2017，Vol.33Issue(6)：1029-1032,4.DOI:10.13463/j.cnki.cczyy.2017.06.057
银屑病动物模型的研究进展
Advances in psoriasis-like animal models
摘要
Abstract
Psoriasis is a chronic recurrent inflammatory dermatosis involved in genetic, immune, infection and other factorse, which etiology and pathogenesis is not yet fully clear. In clinical studies, animal models are widely used.Through reviewing the related papers and summarizing the current psoriasis animal models with analyzing their respective principles, characteristics, advantages and limitations, we get the conclusion that spontaneous mutant rat models are rarely used in research; biomedical animal models are widely used in the evaluation of drug efficacy;drug-induced animal models are suitable for general laboratories; genetic engineering animal models are suitable for conditional workers. Allogeneic animal model is limited by the objective conditions to promote the application;TCM syndrome type psoriasis-like animal model is suitable for the study of Chinese medicine workers. Therefore researchers need to properly select the experimental model according to the purpose of their study and characteristics of animal models.关键词
银屑病/动物模型/中医证型Key words
psoriasis/animal models/TCM patterns分类
医药卫生引用本文复制引用
杨素清,李东东,闫景东..银屑病动物模型的研究进展[J].长春中医药大学学报,2017,33(6):1029-1032,4.基金项目
国家自然科学基金委员会资助项目(81373639). （81373639）
