重庆医学2017，Vol.46Issue(32)：4553-4555,3.DOI:10.3969/j.issn.1671-8348.2017.32.026
混合痔危险因素的病例对照研究
A case-control study on the risk factors of mixed hemorrhoid
摘要
Abstract
Objective To investigate major risk factors of mixed hemorrhoid,and provide scientific basis for primary prevention of the disease.Methods A hospital-based 1:1 matched case-control study method was adopted.A total of 341 patients who were diagnosed with mixed hemorrhoid in the Department of Anorectal Diseases,the Affiliated Hospital of Chengdu University of Traditional Chinese Medicine from June 2015 to February 2016 was recruited as case group.Another 341 non-mixed-hemorrhoid patients with the same gender proportion and age difference within 5 years old were taken as control group.Self-designed questionnaires were applied to face-to-face interview these subjects.The questionnaires included occupational factors,living habits,defecation related factors,disease history,reproductive history,family history and basic knowledge of mixed hemorrhoid.SPSS 20.0 software was used for single-factor analysis.Results It turned out that the factors related to occurrence of hemorrhoid were as followed:education level(x2 =15.431),working position(x2 =18.078),duration of single working position(OR=3.345),alcohol intake(OR=3.269),smoking(OR=1.852),spicy food intake(OR =2.409),less physical exercise(OR =1.522),defecation posture(OR =1.750),defecation time(x2 =7.516),defecation frequency(x2 =8.405),stool shape(x2 =8.004),obesity(OR=1.618),reproductive history(OR=2.211) and hemorrhoid family history of first-degree relatives(OR=1.763);The correlation intension (OR value) between anal fissure,anal pruritus and mixed hemorrhoid was 0.564 and 2.714 respectively;While tea drinking,perianal abscess or anal fistula were in no relation to mixed hemorrhoid onset.Conclusion The onset of mixed hemorrhoid is resulted from joint efforts of occupational factors,living habits,defecation habits and reproductive history,etc.Anal fissure,history of anal pruritus and preanal eczema are closely related to mixed hemorrhoid,and genetic factors may get involved as well.关键词
混合痔/危险因素/1∶1匹配/病例对照研究Key words
mixed hemorrhoid/risk factors/1 ∶ 1 match/case-control study分类
医药卫生引用本文复制引用
杜勇军,黄德铨,杨洁,陈敏,程英杰,王栩芮,黄粲宸,周策..混合痔危险因素的病例对照研究[J].重庆医学,2017,46(32):4553-4555,3.基金项目
国家自然科学基金面上项目(81373644) （81373644）
四川省干部保健科研课题项目(川干研2015-502) （川干研2015-502）
四川省中医药管理局项目(2016C075). （2016C075）
