重庆医学2017，Vol.46Issue(33)：4644-4646,3.DOI:10.3969/j.issn.1671-8348.2017.33.013
CT引导下125I粒子植入联合化疗治疗非小细胞肺癌的疗效分析
Effect analysis of CT-guided 125 iodine seed implantation combined with chemotherapy in treatment of non-small cell lung cancer
摘要
Abstract
Objective To investigate the value of CT guided 125 I seed implantation combined with chemotherapy in the treat-ment of unresectable non-small cell lung cancer .Methods The related data of 42 cases of middle and advanced non-small cell lung cancer treated in this hospital from January 2012 to December 2016 were retrospectively analyzed .The group A (23 cases) received the 125I seed implantation combined with chemotherapy ,while the group B(19 cases) adopted the simple chemotherapy .All cases conducted the chest CT re-examination at 1 ,2 ,6 months after treatment .The curative effects and complications were compared be-tween the two groups .Results The total effect rate (RR) at 1 ,2 ,6 months had statistical difference between the two groups (P<0 .05) .The adverse reactions in the group A were small ,large amounts of pneumothorax (26 .1% ,6/23) ,bone marrow suppression (26 .1% ,6/23) ,nausea and vomiting(30 .4% ,7/23) ,which in the group B were d 5 .3% (1/19) in the group B were bone marrow suppression (36 .8% ,7/19) ,nausea and vomiting (26 .3% ,5/19) .No severe complications were observed .The occurrence rate of adverse reactions had no statistical difference between the two groups (P>0 .05) .The adverse reactions were improved after symp-tomatic treatment .Conclusion CT guided 125 I seed implantation combined with chemotherapy has higher effective rate and more significant effect in treating unresectable non-small cell lung cancer .关键词
癌,非小细胞肺/125I粒子植入/化疗Key words
carcinoma,non-small cell lung/125 I seed implantation/chemotherapy分类
医药卫生引用本文复制引用
何枫,郎伟思,吴小明,赖光湖,郭敏,胡奎,刘恒,杨龙..CT引导下125I粒子植入联合化疗治疗非小细胞肺癌的疗效分析[J].重庆医学,2017,46(33):4644-4646,3.基金项目
重庆市卫生和计划生育委员会基金资助项目(2012-1-116). （2012-1-116）
