摘要
Abstract
Objective To investigate the clinical effect of debridement combined with negative pressure closed drainage (VSD) in the treatment of perianal necrotizing fasciitis.Methods 60 patients of perianal necrotizing fasciitis in our hospital were randomly assigned to treatment group (debridement combined VSD) and control group (simple debridement).The operative indices (operation time,intraoperative blood loss,debridement times,time to body temperature returned to normal,wound healing time,hospital stays) and anal function were compared between the two groups.The prognosis was observed after 1-year follow-up.Results There was no significant difference between the two groups in operation time and intraoperative blood loss (P > 0.05).Debridement times in the treatment group was (1.96±0.87) times less than in the control group.Time to body temperature returned to normal [(11.39±3.26) d],wound healing time[(53.12±9.65) d],hospitalization time[(59.87±6.52) d] in the treatment group were shorter than in the control group(P < 0.05).There was no significant difference in anal rest pressure and anal maximum systolic pressure between the two groups (P > 0.05).The complication rate and mortality rate did not differ between the two groups (P > 0.05).Conclusion Debridement combined with VSD drainage and simple operation in the treatment of perianal necrotizing fasciitis did not affect the anal function,and had comparable effect in improving prognosis.But Debridement combined with VSD drainage can significantly shorten the time body temperature returned to normal,the wound healing time,hospitalization time,and reduce the number of debridement.It can help to promote the recovery of patients and has value for clinical application.关键词
清创术/VSD引流术/肛周坏死性筋膜炎Key words
debridement/VSD drainage/perianal necrotizing fasciitis分类
医药卫生