中医学报2017，Vol.32Issue(11)：2221-2225,5.DOI:10.16368/j.issn.1674-8999.2017.11.578
中医“三调”综合疗法联合普拉克索治疗不安腿综合征临床研究
Clinical Efficacy of "Three Adjustment comprehensive Therapy" Combined with Pramipexole in Treatment of Restless Legs Syndrome
摘要
Abstract
Objective:To observe the clinical curative effect of traditional Chinese medicine " Three Adjustment Comprehensive Therapy"(adjusting Ying and Wei,adjusting Qi and Blood and adjusting Triple burners) combined with western medicine Pramipexole in treatment of restless leg syndrome.Methods:Fifty patients who met the criteria were randomly divided into control group and treatment group(n =25).The control group was treated with oral administration of pramipexole.The treatment group was treated with Chinese medicine functioning in adjusting Ying and Wei,adjusting Qi and Blood and adjusting Triple burners(White peony root 30 g,Guizhi 10 g,Codonopsis 15 g,Angelica 20 g,Salvia 30 g,Safflower 15 g,30 g,Bupleurum 12 g,Scutellaria 15 g,Acacia 30 g,Fried jujube keme 20 g,Prepared Liquorice Root l0 g).In addition,acupuncture treatment was used in the treatment grouop.The acupuncture points are:Shan zhong,zhong wan,Qi hai,Wai guan,Zu sanli and Xuehai.Both groups were treated for 2 months.After treatment,the clinical efficacy,the severity of the patients before and after treatment,quality of life evaluation,sleep quality evaluation,anxiety and depression of both groups were compared.Results:In the treatment group of 25 cases,15 cases were cured,6 cases were markedly effective,3 cases were effective and 1 case was ineffective,with the effective rate being 96.0％.In the control group of 25 cases,6 cases were cured,10 cases were markedly effective,5 cases were effective and 4 cases were ineffective,with the effective rate being 84.0％.There was significant differences between the two groups (P ＜ 0.01).The RLS-Quality of Life scores were significantly higher in the two groups was significantly higher than those of the patients(P ＜ 0.01).After treatment,the two groups of patients can significantly reduce the awake time after sleep,micro arousal index,sleep staging frequency,wake frequency,and the treatment group was significantly better than the control group,the difference was statistically significant (P ＜0.01).The BAI score and BDI score of both groups were significantly lower in the two groups,the difference between the both groups was statistically significant(P ＜0.01).Conclusion:The combination of traditional Chinese medicine "Three Adjustment Comprehensive Therapy" (adjusting Ying and Wei,adjusting Qi and Blood and adjusting Triple burners) combined with western medicine Pramipexole can significantly improve the clinical symptoms,improve the quality of life of patients,improve the overall sleep quality,improve patients' sleep continuity and stability,relieve the patient's anxiety and depression symptoms and adjust patients' mental state.关键词
不安腿综合征/调营卫/调气血/调三焦/普拉克索/中医药疗法/中西医结合Key words
restless legs syndrome/adjusting Ying and Wei, adjusting Qi and Blood and adjusting Triple burners/Pramipexole/traditional Chinese medicine therapy/Integrative medicine分类
医药卫生引用本文复制引用
张志军,王宝亮,赵铎,王丹..中医“三调”综合疗法联合普拉克索治疗不安腿综合征临床研究[J].中医学报,2017,32(11):2221-2225,5.基金项目
河南省中医药科研基金项目(2013ZY03005) （2013ZY03005）
