四川中医2017，Vol.35Issue(10)：61-63,3.
香砂六君子汤合艾箱灸对脾虚型慢性萎缩性胃炎大鼠胃动素影响的实验研究
Experimental Study on the Effect of Xiangsha Liujunzi Decoction Plus Moxa on Motilin for Rats with Spleen Deficiency Type Chronic Atrophic Gastritis
摘要
Abstract
Objective:To observe the effect of herbs and moxibustion on motilin in rats with chronic atrophic gastritis (CAG) in order to explore its mechanism.Methods:Sixty-five SD rats were evenly and randomly divided into controlled group,node1group,herbs group,herbs and Weifuchun group,herbs and moxibustion group.CAG model was established by feeding the rats with MNNG solution,and oxygen bile acid sodium solution every other day,and hunger alternate methd continuously for 8weeks.Herbs cont-ained Dangshen (Radix Oedonopsis Pilosulae),Baizhu (Rhizoma Atractylodis Macrocephalae),Fuling (Poria cocos),Muxiang (Radix Aucklandiae),Sharen (fructus amomi),Gancao (licorice root),Faxia (Rhizoma Pinellinae Praeparata),Chenpi (Pericarpurn Citri Retioulatae),etc.Plasma motilin contents were determined with Elisa Radioi-mmuno-assay.Results:In comparison with the controlled group,plasna motilin content increased significantly in the model group (P＜0.05);while compared with the model group,plasma motilin contents in three treatment groups decreased significantly;In three treatment groups,plasma motilin was lowest in herbs and Weifuchun group,and then herbs and moxibustion groups and herbs groups.Conclusion:Herbs and moxibustion can apparently regulate the levels of plasma motility in CAG rats,produce normal gastrointestinal peristalsis and promote gastric emptying to shorten gastric retention of the damage factor,and thus have effect of gastrointestinal scavenger,which can play role in prevention and treatment of chronic atrophic gastritis.关键词
慢性萎缩性胃炎/香砂六君子汤合艾箱灸/胃肠动力/胃动素/实验研究Key words
Chronic atrophic gastritis/Herbs and moxibustion/Gastrointestinal/Motility/Motilin/Experimental study分类
医药卫生引用本文复制引用
李玉玲,吴庆和,黄穗平..香砂六君子汤合艾箱灸对脾虚型慢性萎缩性胃炎大鼠胃动素影响的实验研究[J].四川中医,2017,35(10):61-63,3.基金项目
广东省科技厅项目(编号:20131B022000090) （编号:20131B022000090）
