摘要
Abstract
Objective:To evaluate the association of pleural tags with visceral pleural invasion of non-small cell lung cancer (NSCLC)that does not abut the pleural. Methods:138 patients of NSCLC that does not abut the pleura were retrospectively analyzed. The pleural tags were classified into three types:type 1,one or more linear pleural tags;type 2,one or more linear pleural tags with soft tissue cord-like pleural end;type 3,one or more soft tissue cord-like pleural tags,and prioritized into type 3,2 and 1 when more than one types were present. The pathologic analysis staged pleural invasion according to the TNM stag-ing system(7th Ed)as follows:PL0,no pleural involvement;PL1,tumor invasion to the elastic layer of the visceral pleura but without reaching the visceral pleural surface;PL2,tumor invasion to the visceral pleural surface;PL3,tumor invasion to the pari-etal pleura or chest wall. Positive likelihood ratio,diagnostic accuracy,sensitivity,specificity,positive and negative predictive value were calculated. Results:The results of pleural tags were following:27 cases(19.6%)absent,59 cases(42.8%)in type 1,21 cases (15.2%)in type 2 and 31 cases(22.5%)in type 3. The results of staged pleural invasion were following:95 cases(68.8%)in PL0,21 cases(15.2%)in PL1,22 cases(16.0%)in PL2,0 case in PL3. In the absence of pleural tags,no pleural invasion was found. In the pleural tags,pleural invasion was found in 43 cases(38.7%). The presence of type 2 pleural tags was moder-ately associated with visceral pleural invasion (accuracy 70.8%). Type 1 pleural tags provided weak evidence to rule out vis-ceral pleural invasion. Type 3 pleural tags indicated minimum correlation to visceral pleural invasion. Conclusions:Type 2 pleural tags can be used as the basis for prediction of visceral pleura invasion in NSCLC that does not abut the pleura. This method is a view to the surgeon to good timing of surgery,thereby improving the life quality of patients with NSCLC that does not abut the pleura. This method is simple and easy to grasp and suitable for promotion in primary medical institutions.关键词
胸膜标记/体层摄影术,X线计算机/胸膜/癌,非小细胞肺Key words
Pleural tags/Tomography,X-ray computed/Pleural/Carcinoma,non-small-cell lung
