中国卒中杂志2017，Vol.12Issue(11)：991-994,4.DOI:10.3969/j.issn.1673-5765.2017.11.004
沙漠化地区缺血性脱髓鞘性脑白质病变危险因素研究
Study on Ischemic Demyelinating Cerebral White Matter Lesions Related Risk Factors in Desertification Areas
摘要
Abstract
Objective To study the risk factors of ischemic demyelinating cerebral white matter lesions in Wuwei desert area retrospectively, so as to provide a theoretical evidence for the clinical prevention of occurrence of ischemic demyelinating cerebral white matter lesions in desert area . Methods A total of 500 patients with ischemic cerebrovascular diseases were selected from the department of neurology of wuwei people's hospital from January 2011 to December,2015. The screened cases were analyzed according to different living places and different risk factors. Multivariate logistic regression was used to analyze the risk factors associated with ischemic demyelinating white matter lesions. Results In desert group, ischemic demyelinating brain white matter disease incidence rate was 62.4%;while in plain group, the ischemic demyelinating leukoencephalopathy incidence rate was 49.6%. In desert group, cerebral white matter severe lesions was 22.4%; in plain group , cerebral white matter severe lesions was 8.4%. Multivariate analysis showed that desertification weather, smoking, alcohol consumption, diabetes mellitus, hypertension, lipid metabolism abnormality, carotid atherosclerosis and homocysteine were risk factors for aggravation of ischemic brain white matter lesions. Conclusion The incidence of ischemic demyelinating white matter lesions in desert areas was higher than that in plain areas, and majority of them were severe lesions.关键词
沙漠化/缺血性脑血管病/白质病变/危险因素Key words
Desertification/Ischemic cerebrovascular diseases/White matter lesions/Risk factors引用本文复制引用
彭炜,张兆耘,殷秀萍,王玉梅..沙漠化地区缺血性脱髓鞘性脑白质病变危险因素研究[J].中国卒中杂志,2017,12(11):991-994,4.基金项目
2016年度武威市科技进步项目(WW160213) （WW160213）
