摘要
Abstract
Objective To explore the influence factors of one-year stroke recurrence in patients with ischemic cerebrovascular disease of symptomatic isolated intracranial arterial stenosis. Methods A total of 86 patients with symptomatic isolated intracranial atherosclerotic stenosis confirmed by the digital subtraction angiography (DSA) were followed up for 1 year. The major outcome was stroke events. The characteristics of distribution of intracranial arterial stenosis were analyzed. The multiple Cox regression analysis was used to evaluate the association between the risk factors including age, gender, hypertension, diabetes, smoking, drinking alcohol, high sensitive creative protein (hsCRP), number of arteriostenosis, stenosis degree, anterior and posterior circulation, ischemia types, history of atherosclerosis of coronary artery, ischemic cerebrovascular diseases, and the outcome. Results The results showed that intracranial artery stenosis mostly occurred in the middle cerebral artery (35.51%). A total of 80 patients who met the criteria were followed up for 1 year. Multifactors Cox regression analysis showed that age≥60 years old [risk ratio (RR) 2.628, 95% confidence interval(CI)1.066-6.478,P=0.036],female(RR 2.645,95% CI 1.133-6.178,P=0.025), National Institutes of Health Stroke Scale (NIHSS) score >1 (RR 3.644, 95% CI 1.280-10.369, P=0.015)and multiple intracranial arterial stenosis(RR 2.712,95% CI 1.048-7.019,P=0.040)were risk factors of endpoint events . Conclusion Age, gender, NIHSS score and the number of intracranial arterial stenosis of patients with ischemic cerebrovascular disease of symptomatic isolated intracranial arterial stenosis may be the predictors of stroke recurrence within one year.关键词
颅内动脉狭窄/缺血性脑血管病/数字减影血管造影/危险因素/预后Key words
Intracranial arterial stenosis/Ischemic cerebrovascular disease/Digital subtraction angiography/Risk factors/Prognosis
