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丁苯酞注射液对急性脑梗死疗效观察

李春祥 赵丽霞 覃华宏

中国卒中杂志2017,Vol.12Issue(11):1010-1012,3.
中国卒中杂志2017,Vol.12Issue(11):1010-1012,3.DOI:10.3969/j.issn.1673-5765.2017.11.008

丁苯酞注射液对急性脑梗死疗效观察

Clinical Efficacy Observation of Butylphthalide Injection on Patients with Acute Ischemic Stroke

李春祥 1赵丽霞 1覃华宏1

作者信息

  • 1. 530003 南宁 武警广西总队医院内一科
  • 折叠

摘要

Abstract

Objective To observe and explore the efficacy of butylphthalide injection on patients with acute cerebral infarction. Methods A total of 128 patients who were diagnosed with acute cerebral infarction and hospitalized in our hospital from February 2013 to December 2014 were randomly selected as study subjects. There were 75 cases in conventional group and 53 cases in the group of conventional therapy combined with butylphthalide peptide sodium chloride injection. The neurological impairment, the level of high sensitivity C-reactive protein (hsCRP) and lysophosphatidic acid (LPA) in two groups before and after treatment were compared. Results There was no significant difference in National Institutes of Health stroke scale (NIHSS) between two groups before treatment. The scores of NIHSS of two groups after treatment both decreased significantly comparing with that of respective group before treatment. The NIHSS score of treatment group was significantly lower than that of conventional group. The hsCRP and LPA levels of two groups after treatment decreased significantly than that of respective group before treatment, and the levels in treatment group were significantly lower than that in conventional group. Conclusion Butyphthalide injection combined therapy had better effect in reducing neurological deficit, hsCRP level and LPA level in patients with acute cerebral infarction comparing with conventional therapy.

关键词

丁苯酞/脑梗死/预后/炎性因子

Key words

Butylphthalide/Cerebral infarction/Prognosis/Inflammatory factor

引用本文复制引用

李春祥,赵丽霞,覃华宏..丁苯酞注射液对急性脑梗死疗效观察[J].中国卒中杂志,2017,12(11):1010-1012,3.

中国卒中杂志

OACSTPCD

1673-5765

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