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蛛网膜下腔出血后神经炎症反应的研究进展

王永朋 张彤宇 张广 徐善才 郑秉杰 史怀璋

中国卒中杂志2017,Vol.12Issue(11):1061-1066,6.
中国卒中杂志2017,Vol.12Issue(11):1061-1066,6.DOI:10.3969/j.issn.1673-5765.2017.11.016

蛛网膜下腔出血后神经炎症反应的研究进展

Research Advance in Neurogenic Inflammation Induced by Subarachnoid Hemorrhage

王永朋 1张彤宇 1张广 1徐善才 1郑秉杰 1史怀璋1

作者信息

  • 1. 150001 哈尔滨 哈尔滨医科大学附属第一医院神经外科三病房
  • 折叠

摘要

Abstract

Aneurysmal subarachnoid hemorrhage (aSAH) was a common cerebrovascular disease. With the improvement of clinical surgical technology, the aneurysms can be treated and the mortality caused by rehaemorrhagia decreased, while there were few effective therapeutic measures in allusion to subarachnoid hemorrhage. It was known that neuroinflammation response played a critical role in pathological process after subarachnoid hemorrhage. Studies had shown that inflammation was associated with vasospasm and brain injury. Many preclinical studies had been conducted to explore the correlation between neuroinflammation and aSAH, and the researchers found that inflammatory mediator played an important role in this process. This article provided an overview of the neuroinflammation after aSAH and its pathogenic mechanism.

关键词

动脉瘤性蛛网膜下腔出血/脑血管痉挛/神经炎症反应/迟发性脑缺血

Key words

Aneurysmal subarachnoid hemorrhage/Cerebral vasospasm/Neuroinflammation response/Delayed cerebral ischemia

引用本文复制引用

王永朋,张彤宇,张广,徐善才,郑秉杰,史怀璋..蛛网膜下腔出血后神经炎症反应的研究进展[J].中国卒中杂志,2017,12(11):1061-1066,6.

基金项目

国家青年科学基金项目(81100854) (81100854)

中国卒中杂志

OACSTPCD

1673-5765

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