中华耳科学杂志2017，Vol.15Issue(5)：575-579,5.DOI:10.3969/j.issn.1672-2922.2017.015.
MicroRNA调控神经突触囊泡循环的研究进展
Progress of Research on MicroRNA in Regulating Synaptic Vesicle Recycling
摘要
Abstract
MicroRNAs (miRNAs) are a class of small22 nucleotides noncoding RNAs that regulate the expres-sion of genes based on the transcription of mRNA and the negative control of stability. miRNAs are abundant in the brain, where they play key roles in neuron growth and development and in regulation of neural function. Neurotransmis-sion begins with the release of neurotransmitters from synaptic vesicles. Synaptic vesicles endure the dynamic "re-lease-recycle"process to maintain the function and structure of presynaptic terminal. Advancing research has found that miRNA plays an significant role in neural synapsing. This review focuses on miRNAs in regulating synaptic vesicle re-cycling .关键词
microRNA/突触/带状突触/囊泡循环Key words
MicroRNA/Synapse/Ribbon Synapse/Vesicle Cycle分类
医药卫生引用本文复制引用
唐小林,袁伟..MicroRNA调控神经突触囊泡循环的研究进展[J].中华耳科学杂志,2017,15(5):575-579,5.基金项目
国家自然基金资助,项目编号:81470694、81271080 （）
重庆市科委民生专项资助,项目编号:cstc2016shmszx130058 （）
西南医院院管课题,项目编号:JCZD-39.This study was supported by the National Natural Science Foundation of China(81470694、81271080),Chongqing Municipal Sci-ence and Technology Commission of the people's livelihood special funding(cstc2016shmszx130058),and the project of Southwest Hos-pital(JCZD-39). （81470694、81271080）
