中成药2017，Vol.39Issue(11)：2345-2350,6.DOI:10.3969/j.issn.1001-1528.2017.11.027
21个产地七叶一枝花中皂苷类成分的评价
Evaluation of saponins in Paris Polyphylla var.chinensis from twenty-one growing areas
摘要
Abstract
AIM To evaluate saponins in Paris Polyphylla Smith var.chinensis (Franch.) Hara from twentyone growing areas.METHODS HPLC was adopted in the content determination of pennogenins { pennogenin-3-O-β-D-glu (1→3) [α-L-rha (1→2)]-β-D-glu (PGGR),polyphyllinsⅥ,Ⅶ,H} and dioscins (gracillin,polyphyllins Ⅰ,Ⅱ,Ⅴ),then SPSS 22.0 software was used for principal component analysis and cluster analysis.RESULTS Pennogenin was the main kind of Paris Polyphylla var.chinensis saponins,and PGGR,polyphyllins Ⅰ,Ⅴ,Ⅶ,H were the main effective constituents of this medicinal material.The comprehension scores of seven growing areas were more than zero,which was in sequence of Bazhong ＞ Qingchuan ＞ Yanjin ＞ Tongjiang ＞ Nanchuan ＞ Chongzhou ＞ Hongya.Twenty-one batches of samples were divided into four types,which was similar to cluster analysis results.CONCLUSION Bazhong,Qingchuan,Chongzhou,Hongya,Tongjiang in Sichuan,Yanjin in Yunnan,and Nanchuan in Chongqing are suitable for cultivating Paris Polyphylla var.chinensis,which can guarantee the stability of saponins.关键词
七叶一枝花/皂苷/产地/HPLC/主成分分析/聚类分析Key words
Paris Polyphylla Smith Var.Chinensis (Franch.) Hara/saponins/growing areas/HPLC/principal component analysis/cluster analysis分类
医药卫生引用本文复制引用
陈铁柱,文飞燕,张涛,杨玉霞,方清茂,张浩,薛丹..21个产地七叶一枝花中皂苷类成分的评价[J].中成药,2017,39(11):2345-2350,6.基金项目
中央本级重大增减支项目(2060302) （2060302）
四川省中医药管理局科技专项(2010-46) （2010-46）
四川省科技厅应用基础研究(2016JY0081) （2016JY0081）
四川省公益性科研院所基本科研业务专项(2016YSKY0084) （2016YSKY0084）
四川省科技厅科技扶贫专项(2016NFP0073) （2016NFP0073）
四川省科技厅科技创新苗子工程项目(2017RZ0051) （2017RZ0051）
