肿瘤防治研究2017，Vol.44Issue(11)：740-744,5.DOI:10.3971/j.issn.1000-8578.2017.17.0666
胸腹腔镜联合与传统开胸术治疗高龄食管癌患者(≥70岁)的临床比较
Clinical Comparison of Minimally Invasive Esophagectomy Versus Open Esophagectomy on Elderly Esophageal Carcinoma Patients (≥ 70 Years Old)
佘晓伟 1赵军 2徐春 1李畅 1丁成 1陈俊 1龚永生1
作者信息
- 1. 215006苏州,苏州大学附属第一人民医院胸外科
- 2. 215008苏州,南京医科大学附属苏州市立医院北区胸外科
- 折叠
摘要
Abstract
Objective To compare the clinical effect of minimally invasive esophagectomy(MIE) versus open esophagectomy (OE) on elderly esophageal carcinoma patients(≥ 70 years old),to provide the relevant theoretical basis for the clinical application of minimally invasive surgery on esophageal carcinoma.Methods We retrospectively reviewed the data of the randomly-selected elderly patients who underwent MIE or OE(each 52) in the Department of Thoracic Surgery.Results The MIE group was successfully performed under thoracoscopy and laparoscopy without conversion to open esophagectomy.The mean operation time were (261.4±35.2) and (249.0±37.0)min in MIE and OE groups (P＞0.05).The intraoperative blood loss on average were respectively about (190.1±86.8) and (391.35±118.5)ml in MIE and OE groups(P＜0.05).The white blood cell(WBC),C-reactive protein(CRP) and postoperative pain evaluation were better in the MIE group than those in the OE group (P＜0.05).There was no significant difference in anastomotic fistula,recurrent laryngeal nerve injury or chylothorax between the two groups,but the incidence of pulmonary infection,respiratory failure and arrhythmia in MIE group was lower than those in OE group (P＜0.05).The hospitalization time in MIE group was less than that in OE group (P＜0.05).The patients were followed up for (22.1±11.1) months,there was no significant difference in survival time between the two groups (P=0.985).Conclusion Clinical application of MIE could significantly reduce the elderly patients' postoperative pain,systemic inflammatory response,the incidence of complications such as cardiopulmonary system,as well as the length of hospital stay.It is conducive to rapid recovery of elderly esophageal cancer patients.关键词
高龄/食管癌根治术/微创/开胸术/食管癌Key words
Elderly/Esophagectomy/Minimally invasive/Thoracotomy/Esophageal carcinoma分类
医药卫生引用本文复制引用
佘晓伟,赵军,徐春,李畅,丁成,陈俊,龚永生..胸腹腔镜联合与传统开胸术治疗高龄食管癌患者(≥70岁)的临床比较[J].肿瘤防治研究,2017,44(11):740-744,5.
