中药材2017，Vol.40Issue(5)：1061-1065,5.DOI:10.13863/j.issn1001-4454.2017.05.012
基于指纹图谱和化学计量学的丹参及紫丹参质量评价研究
Species Differentiation and Quality Assessment of Salvia miltiorrhiza and Salvia trijuga by HPLC Fingerprint
摘要
Abstract
Objective:To establish HPLC fingerprint for identification of Salvia miltiorrhiza and Salvia trijuga.Methods:An HPLC method was developed to establish the fingerprint,and Hierarchical Cluster Analysis (HCA)and Principal Component Analysis (PCA)were applied to study HPLC fingerprint and chemical recognition.Results:There existed large difference of chromatographic peaks and its relative peak area of HPLC fingerprints between Salvia miltiorrhiza and Salvia trijuga.Combining with chemometric methods,the results demonstrated that all samples were classified into two categories.Conclusion:Chemical pattern expressed by HPLC fingerprint analysis can play an important role in species differentiation and quality control of Salvia miltiorrhiza.关键词
丹参/紫丹参/HPLC/指纹图谱/化学计量学Key words
Salvia miltiorrhiza Bge./Salvia trijuga Diels/HPLC/Fingerprint/Chemometric分类
医药卫生引用本文复制引用
张晓灿,罗丹丹,陶爱恩,夏从龙,段宝忠..基于指纹图谱和化学计量学的丹参及紫丹参质量评价研究[J].中药材,2017,40(5):1061-1065,5.基金项目
国家自然科学基金(31460086) （31460086）
云南省中青年学术技术带头人后备人才项目(2015HB058) （2015HB058）
云南省教育厅科学研究基金(2014Z135) （2014Z135）
