重庆医学2017，Vol.46Issue(34)：4763-4765,4770,4.DOI:10.3969/j.issn.1671-8348.2017.34.003
聚焦超声对兔耳痤疮的治疗效果研究
Therapeutic effect of focused ultrasound on rabbit ear acnevv
摘要
Abstract
Objective To investigate the feasibility and effectiveness of focused ultrasound on the acne of rabbit ear.Methods Eighteen male rabbits were randomly divided into blank control group,model control group and ultrasound irradiation group.Acne rabbit ear model was established by Kligman's method in model control group and ultrasound irradiation group.Then,continuous ultrasonic irradiation was given in ultrasound irradiation group.Pathological changes were observed at the time of before and after ultrasound irradiation and 14 days after ultrasound irradiation.Results After modeling,hair follicle expansion,hyperkeratosis,acupoint hypertrophy were observed in blank control group.Compared with blank control group,the thickness of horn layer,the sebaceous gland diameter and other index in model controlgroup were statistically significant (P＜0.01);After irradiation,there were hyperemia and edema in epidermis,angiotelectasis and inflammatory infiltrating,but coagulative necrosis in slice was not observed,14 days later,hair follicle mild expansion,mild keratosis,spiny thinning were observed in ultrasound irradiation group,when compared with model control group,the thickness of horn layer,sebaceous gland diameter and other index were decreased in ultrasound irradiation group,and the differences were statistically significant(P＜0.01).Conclusion The ultrasonic focusing treatment on rabbit ear acne is feasible and effective.关键词
聚焦超声/兔耳痤疮/疗效Key words
focused ultrasound/rabbit ear acne/effectiveness分类
医药卫生引用本文复制引用
董小勇,郭张有,李清仪,刘运畅,田瑜,钟芳莹,邹建中..聚焦超声对兔耳痤疮的治疗效果研究[J].重庆医学,2017,46(34):4763-4765,4770,4.基金项目
国家重点基础研究发展计划(973计划)项目(2011CB707900) （973计划）
国家重大科学仪器设备研制专项资助项目(81127901). （81127901）
