摘要
Abstract
Objective:To investigate the therapeutic effects and immune function of Xiyanping combined with azithromycin in treatment of severe Mycoplasma pneumoniae pneumonia (MPP) in children.Methods:Eighty severe MPP children treated in our hospital From January 2014 to June 2016 were selected,randomly divided into observation group and control group,40 cases in each group.While the control group was given azithromycin treatment,the observation group was given azithromycin and Xiyanping injection.The clinical effects and the clinical symptoms of the two groups were compared.The T lymphocyte subsets (CD3+,CD4+,CD8+,CD4+/CD8+)were compared between the two groups before and after treatment.Results:The total effective rate was 95.0％ in the observation group,the markedly effective rate was 85.0％,higher than 85.0％ and 67.5％ of the control group.Defervescence time (4.27±1.56) d,cough disappeared time (8.12±2.02) d,rales disappearance time (4.84±1.62) d and chest X-ray absorption time (10.86± 1.87) d in observation group were significantly shorter than the control group (5.16±1.82) d,(9.35±2.62) d,(5.63±1.53) d,(13.28±2.49) d.The differences were significant (P＜0.05).Compared with before treatment,the levels of CD3 +,CD4+,CD4+/CD8+ were significantly increased in the two groups after treatment,while CD8+ decreased significantly.But the improvement degrees of the observation group were significantly better than the control group.The differences were significant (P＜0.05).Conclusion:Xiyanping combined with azithromycin in treatment of Mycoplasma pneumoniae pneumonia in children can significantly improve clinical symptoms,improve the clinical symptoms and regulate immune function in children.关键词
喜炎平/重症/肺炎支原体肺炎/免疫功能Key words
Xiyanping/severe/Mycoplasma pneumoniae pneumonia/immune function分类
医药卫生
