腹腔镜外科杂志2017，Vol.22Issue(11)：855-858,4.DOI:10.13499/j.cnki.fqjwkzz.2017.11.855
新辅助内分泌治疗配合腹腔镜手术治疗高危前列腺癌的疗效及对控尿功能的影响
The therapeutic effect of neo-adjuvant hormone therapy combined with laparoscopic surgery in the treatment of high-risk prostate cancer and its effect on urinary continence
郑保良 1孙国庆 1董山峰 1宋瑞彬 1赵永体 1崔志刚1
作者信息
- 1. 焦作煤业(集团)有限责任公司中央医院,河南焦作,454000
- 折叠
摘要
Abstract
Objective:To observe the therapeutic effect of neo-adjuvant hormone therapy combined with laparoscopic surgery in the treatment of high-risk prostate cancer and the effect on urinary continence.Methods:Eighty-six patients with high-risk prostate cancer were selected and randomly and equally divided into control group and observation group.Control group was treated by laparoscopic radical prostatectomy,and observation group added neo-adjuvant hormone therapy on the basis of the control group.The intraoperative and postoperative indexes,complication incidence,biochemical recurrence rate were observed in the two groups.Results:The operation time and intraoperative bleeding in the observation group were significantly higher than the control group (P ＜ 0.05).Ambulation time,hospital stay,indwelling catheter time and intestinal function recovery time in observation group were significantly less than those in the control group (P ＜ 0.05).The complication incidence of the observation group (13.95％) was significantly lower than that of the control group (32.56％,P ＜ 0.05).Urinary continence rate of the observation group in 3 months and 6 months after surgery was significantly higher than that of the control group (P ＜ 0.05).Biochemical recurrence of observation group in 1 year and 2 years after surgery was significantly lower than that of the control group (P ＜ 0.05).Conclusions:Neo-adjuvant hormone therapy combined with laparoscopic radical prostatectomy can effectively reduce the complications in high-risk prostate cancer and improve urinary continence,but is in need of evaluation of patients before operation.关键词
前列腺肿瘤/腹腔镜检查/新辅助内分泌治疗/治疗结果/控尿Key words
Prostatic neoplasms/Laparoscopy/Neo-adjuvant hormone therapy/Treatment outcome/Urinary continence分类
医药卫生引用本文复制引用
郑保良,孙国庆,董山峰,宋瑞彬,赵永体,崔志刚..新辅助内分泌治疗配合腹腔镜手术治疗高危前列腺癌的疗效及对控尿功能的影响[J].腹腔镜外科杂志,2017,22(11):855-858,4.
