神经损伤与功能重建2017，Vol.12Issue(6)：497-500,4.DOI:10.16780/j.cnki.sjssgncj.2017.06.008
静脉溶栓后早期神经功能改善的急性脑梗死患者预后良好
Patients with Acute Cerebral Infarction with Improved Early Neurological Function after Intravenous Thrombolysis Have a Good Prognosis
徐刚 1张新江 1陈斌 1刘一辉1
作者信息
- 1. 江苏省扬州大学附属医院神经内科 江苏扬州225000
- 折叠
摘要
Abstract
Objective:To evaluate the relationship between the improvement of early neurological function and the prognosis of patients with acute ischemic stroke after onset of 90 d.Methods:All patients underwent thrombolysis prior to thrombolysis with a National Institutes of Health Stroke Scale (NIHSS) score,retrospectively analyzed for acute ischemic stroke and received intravenous thrombolysis with recombinant tissue plasminogen activator (rt-PA),1 h after thrombolysis NIHSS score.The improvement of early neurological function was defined as 1 h after thrombolysis NIHSS score reduction ≥ 5 points or NIHSS score =0,with modified Rankin scale (mRS) score to evaluate the 90 d prognosis.The use of Logistics regression model to analyze the correlation between early neurological improvement and prognosis at 90 days in patients.Results:Ninety-four patients were enrolled in this study.In the first hour after thrombolysis,there were 27 cases (28.72％) of early neurological improvement.Multivariate Logistic regression analysis showed that early neurological improvement was an independent predictor of 90-day good prognosis (OR 6.79;95％ CI 1.73～26.61,P＜0.01).Conclusion:After rt-PA intravenous thrombolysis,acute ischemic stroke patients with early neurological improvement after 90 d had a good prognosis.关键词
急性缺血性卒中/溶栓/预后/早期神经功能改善Key words
acute ischemic stroke/thrombolysis/outcome/early neurologic improvement分类
医药卫生引用本文复制引用
徐刚,张新江,陈斌,刘一辉..静脉溶栓后早期神经功能改善的急性脑梗死患者预后良好[J].神经损伤与功能重建,2017,12(6):497-500,4.
