神经损伤与功能重建2017，Vol.12Issue(6)：523-525,3.DOI:10.16780/j.cnki.sjssgncj.2017.06.016
甘露醇联合糖皮质激素治疗周围性面神经麻痹的疗效观察
The Effect of Treating Peripheral Facial Paralysis Patients with Mannitol Combined with Glucocorticoid
摘要
Abstract
Objective:To observe the clinical efficacy of treating peripheral facial paralysis patients with mannitol combined with glucocorticoid.Methods:One hundred and twenty cases with peripheral facial paralysis were enrolled and were randomly divided into treatment group (n=60) and control group (n=60).Cases in the control group were treated with conventional therapy ways and dexamethasone.Besides conventional therapy ways and dexamethasone,mannitol were used to treat the patients in the treatment group.Data of electromyogram and House-Brackmann scales were collected and compared between the two groups.Results:At 7 days after treatment,the total effective rate was 78.33％ in the treatment group and 56.67％ in the control group (P＜ 0.05).At 14 days after treatment,the total effective rate was 90.33％ in the treatment group and 81.67％ in the control group (P＜0.05).Electromyogram data showed that CMAP amplitude recovered in the both groups and R1 incubation period was shorter than those before.CMAP amplitudes and R1 incubation periods in the treatment group were shorter than those in the control group (P＜0.05).Conclusion:It is an effective way to treat peripheral facial paralysis patients with mannitol combined with glucocorticoid.关键词
周围性面神经麻痹/甘露醇/糖皮质激素/面神经功能指数Key words
peripheral facial paralysis/mannitol/glucocorticoids/facial nerve function index分类
医药卫生引用本文复制引用
谢谢,孙勤国,郭乃燕,江波,徐鸿婕,张贤梅,谢萍,李婵,姚雪婷..甘露醇联合糖皮质激素治疗周围性面神经麻痹的疗效观察[J].神经损伤与功能重建,2017,12(6):523-525,3.基金项目
2016年武汉市卫计委立项课题(No.WZ16D14) （No.WZ16D14）
