华东理工大学学报（自然科学版）2017，Vol.43Issue(5)：640-646,7.DOI:10.14135/j.cnki.1006-3080.2017.05.007
用基团贡献法估算聚乙二醇单甲醚-聚乳酸两亲嵌段共聚物的HLB值
Estimation of Hydrophile-Lipophile Balance for mPEG-PLA by Group Contribution Method
董亚娟 1惠志倩 2戎宗明1
作者信息
- 1. 华东理工大学化学与分子工程学院,上海200237
- 2. 通标标准技术服务(上海)有限公司,上海200233
- 折叠
摘要
Abstract
HLB (Hydrophile-Lipophile Balance) values of methoxy poly (ethylene glycol)-poly (lactic acid) (mPEG-PLA) samples were measured by water number method.A linear relationship was showed between the HLB values and the volume fraction of mPEG (ψEO) in its molecule.The Gamma probability density function (PDF) was used to describe the contribution of single PLA group to HLB,and the effective chain length of PLA chain could be calculated by integrating Gamma PDF.Therefore,HLB of mPEG-PLA can be estimated by group contribution method,and the average absolute error is less than 0.97,which is better than the results calculated by Griffin's method.关键词
亲水-亲油平衡/基团贡献法/有效链长/聚乳酸/聚乙二醇单甲醚-聚乳酸Key words
hydrophile-lipophile balance/group contribution method/effective chain length/poly(lactic acid)/mPEG-PLA分类
化学化工引用本文复制引用
董亚娟,惠志倩,戎宗明..用基团贡献法估算聚乙二醇单甲醚-聚乳酸两亲嵌段共聚物的HLB值[J].华东理工大学学报（自然科学版）,2017,43(5):640-646,7.
