中医药导报2017，Vol.23Issue(22)：39-41,3.
增液汤对实验动物排便及离体肠管的影响研究
Effect of Zengye Decoction（增液汤） on Defecation and Isolated Intestine in Experimental Animal
摘要
Abstract
Objective:To study the effect of Zengye Decoction on defecation,intestinal water absorption for constipation model in mice and isolated intestine in rats.Methods:SPF Kunming mice were divided into the normal group,the model group;the Maren capsule group,the high,the medium and low does Zengye Decoction groups.Constipation mouse model was established by Compound Diphenoxylate tablets.After the establishment of the model,given Zengye Decoction intervention,then study the effect of Zengye Decoction on defecation,intestinal water absorption for constipation model in mice.In vitro method was used to observe the effect of Zengye Decoction on intestine in rats.Results:Compared with the model group,the high and medium dose groups could shorten the first defecation time and increase the number of fecal granules,the difference was statistically significant (P＜0.01).Compared with the model group,the decoction increased the intestinal water content in the constipation model mice,and the difference was statistically significant (P＜0.01).Zengye Decoction can increase the muscle tension of the isolated intestine in rats (P＜0.05),but it has no obvious influence on the movement of the isolated intestinal tract with the receptor blocker.Conclusion:The Zengye decoction has a good effect of relaxing intestines and relaxing bowels,and it can increase the water content and muscle tension in the intestine.关键词
增液汤/便秘/肠道水分/离体肠管/小鼠/大鼠Key words
Zengye Decoction/constipation/intestinal water/isolated intestinal tract/mice/rats分类
医药卫生引用本文复制引用
于凡,熊洪艳,梁玲,杨榆青..增液汤对实验动物排便及离体肠管的影响研究[J].中医药导报,2017,23(22):39-41,3.基金项目
云南省应用基础研究计划项目(2014FZ084) （2014FZ084）
