实用临床医药杂志2017，Vol.21Issue(21)：62-64,3.DOI:10.7619/jcmp.201721018
右美托咪定复合地佐辛超前镇痛在肛肠科吻合器痔上黏膜环切术中的应用
Application of dexmedetomidine combined with preemptive analgesia with dezocine in the treatment of patients with PPH surgery
摘要
Abstract
Objective To investigate the effect of dexmedetomidine combined with the preemptive analgesia with dezocine on the treatment of patients with prolapse and prolapse of hemorrhoids (PPH).Methods A total of 60 patients with PPH were randomly divided into dexmedetomidine + dezocine group (group A) and normal saline + dezocine group (group B).All patients received lowdose saddle anesthesia,and at the time points of saddle anesthesia fixed plane (T0),firing the stapler (T1) and at the end of operation (T2),systolic blood pressure (SBP),diastolic blood pressure (DBP),heart rate (HR),Ramsay sedation score,the incidence of postoperative analgesic effect and complications were compared between two groups.Results At T1 and T2,the SBP,DBP and HR of group A were significantly lower than those of group B (P ＜ 0.05),and the score of Ramsay sedation was significantly higher than that of group B (P ＜ 0.05).The analgesic effect VAS scores of group A at 4,8,12,24 and 48 h after operation were significantly lower than those in group B (P ＜0.05).There was no significant difference in anal distention and discomfort between the two groups (P ＞ 0.05).There were significant differences in the incidence of urinary retention,nausea and vomiting,and nocturnal sleep disorders between the two groups (P ＜ 0.01).Conclusion Dexmedetomidine combined with preemptive analgesia with dezocine is effective in treatment of patients with PPH surgery.关键词
右美托咪定/地佐辛/超前镇痛/吻合器痔上黏膜环切术Key words
dexmedetomidine/dezocine/preemptive analgesia/procedure for prolapse and hemorrhoids分类
医药卫生引用本文复制引用
崔玉沛,刘苏,毛珊珊,曹永,刘静..右美托咪定复合地佐辛超前镇痛在肛肠科吻合器痔上黏膜环切术中的应用[J].实用临床医药杂志,2017,21(21):62-64,3.基金项目
国家自然科学基金资助项目(81371242) （81371242）
