摘要
Abstract
Objective To investigate the treatment effects of radiofrequency ablation on patients with the liver cancer and its effect on serum CRP ,ALT and AST .Methods 92 cases of primary liver cancer were selected ,which were treated in the hospital from February 2015 to February 2016 ,and were divided into the observation group (46 cases) and control group (46 cases) .The patients of observation group were treated with radiofrequency ablation surgery ,while the patients of control group were treated with traditional open surgery .After surgery ,the patients of two groups were all treated with conventional chemotherapy for 4 weeks .The recent clinical efficacy ,and the changes of CRP ,ALT and AST levels on the seventh day before and after the surgery between two groups were compared .The postoperative complications and the 1-year survival rate were observed .Results The total effective rate was 80 .4％ in the observation group and 73 .9％ in the control group ,and the treatment effects were similar .On the seventh day after the surgery ,CRP ,ALT ,AST levels of the observation group were all significantly lower than those of the control group ,and the difference was statistically significant (P<0 .05);but the incidence rate of complications ,such as fever ,infection ,ab-dominal hemorrhage ,moderate to severe ascites ,liver failure ,was significantly lower in the observation group than the one in the control group ,and the difference was statistically significant (P<0 .05) .The patients were followed up for 1 to 12 months (median follow-up time was 7 .2 months);the 1-year survival rate was 28 .4％ in the control group and 60 .3％ in the observation group ,and the difference was statistically significant (χ2 =20 .615 ,P=0 .000) .Conclusion For patients with primary liver cancer ,radiofre-quency ablation has similar treatment effect with the conventional laparotomy ,but has little effects on the stress response of the body and liver function injury .Besides ,it has fewer complications ,and is safe and reliable ,which has an important clinical value .关键词
射频消融术/肝癌/C反应蛋白/丙氨酸氨基转移酶/天门冬氨酸氨基转移酶Key words
radiofrequency ablation/liver cancer/C-reactive protein/alanine aminotransferase/aspartic acid transferase
