临床肝胆病杂志2017，Vol.33Issue(10)：1922-1927,6.DOI:10.3969/j.issn.1001-5256.2017.10.014
胆汁酸的肠肝循环与胆汁淤积性肝病
Association between enterohepatic circulation of bile acid and cholestatic liver disease
李晓峰 1龚敬宇 2王建设1
作者信息
- 1. 复旦大学附属金山医院儿科,上海201508
- 2. 中山大学附属第三医院儿科,广州510630
- 折叠
摘要
Abstract
The development of cholestatic liver disease is closely associated with the enterohepatic circulation disorder of bile acid.This article elaborates on metabolism of bile acid,enterohepatic circulation-related mechanism of hereditary cholestasis,molecular regulation of related transporters,and association between current therapeutic regimens and enterohepatic circulation,in order to investigate the pathogenesis of cholestatic liver disease and provide a basis for the research on new drugs or therapies.关键词
胆酸/肠肝循环/胆汁淤积Key words
cholic acid/enterohepatic circulation/cholestasis分类
医药卫生引用本文复制引用
李晓峰,龚敬宇,王建设..胆汁酸的肠肝循环与胆汁淤积性肝病[J].临床肝胆病杂志,2017,33(10):1922-1927,6.
