临床肝胆病杂志2017，Vol.33Issue(10)：2025-2029,5.DOI:10.3969/j.issn.1001-5256.2017.10.038
儿童非酒精性脂肪性肝病的诊断进展
Research advances in the diagnosis of nonalcoholic fatty liver disease in children
李婧 1戚伶俐 2吴捷1
作者信息
- 1. 中国医科大学附属盛京医院小儿消化科,沈阳110004
- 2. 吉林大学第一医院小儿消化科,长春130012
- 折叠
摘要
Abstract
Nonalcoholic fatty liver disease (NAFLD) has become one of the most common chronic liver diseases in children.Since the clinical manifestations of NAFLD lack specificity,the diagnosis of this disease is mainly based on clinical symptoms and auxiliary examinations.Serum liver enzymes,blood lipid levels and homeostasis model assessment of insulin resistance are commonly used in clinical practice,and cytokeratin-18,triglyceride glucose index may become new markers for the diagnosis of NAFLD in children.Imaging examinations such as ultrasound,magnetic resonance imaging and computed tomography have their own limitations in the diagnosis of NAFLD in children,while controlled attenuation parameter and acoustic radiation force impulse may have a high value in future.The scoring systems for NAFLD need to be validated by clinical research.At present,liver biopsy remains the " gold standard" for the diagnosis of NAFLD in children.This article summarizes the latest research advances in NAFLD in children and discusses the diagnostic values of laboratory markers and imaging examinations.关键词
脂肪肝/诊断/儿童/综述Key words
fatty liver/diagnosis/child/review分类
医药卫生引用本文复制引用
李婧,戚伶俐,吴捷..儿童非酒精性脂肪性肝病的诊断进展[J].临床肝胆病杂志,2017,33(10):2025-2029,5.
