临床口腔医学杂志2017,Vol.33Issue(12):731-734,4.DOI:10.3969/j.issn.1003-1634.2017.12.008
益生菌制剂辅助刮治和根面平整对牙周炎疗效的Meta分析
Effect of probiotics combined with scaling and root planing in the treatment of periodontitis:a meta-analysis
戈春城 1余周庆 1童国勇 1徐佳1
作者信息
- 1. 恩施土家族苗族自治州中心医院口腔诊疗中心 湖北 恩施 445000
- 折叠
摘要
Abstract
Objective:To compare the clinical efficacy of probiotics combined with subgingival scaling and root pla-ning( SRP) versus SRP alone in the treatment of chronic periodontitis. Methods:We systematically searched PubMed, The Cochrane Library,Embase,CNKI and Wanfang databases through January 31,2017 and scrutinized the reference lists of rele-vant literatures. Randomized controlled trials that investigated the clinical effects of probiotics combined with SRP in treating chronic periodontitis were included. Results:Six RCTs were finally included with a total of 205 patients,of whom 103 patients were in the probiotics plus SRP group and 102 patients were in the SRP group. The results of meta-analysis showed that com-pared with SRP alone,probiotics combined with SRP was associated with a decreased periodontal probing depth( PD) and an increased clinical attachment level(CAL). Moreover,probiotics combined with SRP also further reduced plaque index and gingival index in chronic periodontitis patients,without significant influence on bleeding on probing. Conclusion:In the treat-ment of chronic periodontitis,probiotics plus SRP has better clinical efficacy compared with SRP alone.关键词
益生菌/牙周炎/非手术治疗/Meta分析Key words
Probiotics/Periodontitis/Non-surgical therapy/Meta-analysis分类
医药卫生引用本文复制引用
戈春城,余周庆,童国勇,徐佳..益生菌制剂辅助刮治和根面平整对牙周炎疗效的Meta分析[J].临床口腔医学杂志,2017,33(12):731-734,4.