日用化学工业2017，Vol.47Issue(3)：148-152,158,6.DOI:10.13218/j.cnki.csdc.2017.03.006
8种中药提取物在膏霜类化妆品中的抑菌效能研究
Bacterium inhibition efficacy of eight kinds of herbal extract in cream type cosmetics
摘要
Abstract
Extracts of eight kinds of herb (clove,houttuynia,Polygonum cuspidatum,Coptis chinensis,rhubarb, asarum,licorice and scutellaria)were prepared by cellulase method;and their bacterium inhibition efficacy was studied by disc diffusion method and test tube broth dilution method. Formulation study based upon the bacterium inhibition of the aforesaid preservatives was conducted. With reference of the bacterium inhibition efficacy test method of American Personal Care Product Committee (PCPC ),microbial challenge tests for cream formulation was processed. The test results demonstrated that in the eight kinds of herbal extract,the extract of Coptis chinensis shows best efficacy on Staphylococcus aureus,Pseudomonas aeruginosa and Escherichia coli. Its diameter of inhibition zone is (12. 4 ± 0. 4 ),(11. 4 ± 0. 6 )and (10. 7 ± 0. 2 )mm respectively,and the minimum inhibitory concentration (MIC)is 31. 25,31. 25 and 15. 625 g/L respectively. When the mass fraction of the extract of Coptis chinensis and scutellaria in cream formula is 0. 8％ and 0. 6％ respectively,it can inhibit the growth of bacteria and fungi effectively and pass the microbial challenge test meanwhile.关键词
化妆品/中药提取物/抑菌效能/纤维素酶Key words
cosmetics/herbal extract/bacterium inhibition efficacy/cellulase分类
化学工程引用本文复制引用
区梓聪,何秋星,陈佩,方电力..8种中药提取物在膏霜类化妆品中的抑菌效能研究[J].日用化学工业,2017,47(3):148-152,158,6.基金项目
2015年广东药科大学"创新强校工程人才培养模式创新实验区"资助项目(gyzlgc201503 ) （gyzlgc201503 ）
广东省化妆品工程技术研究中心资助项目 （）
2015年广东药科大学校级教育教学成果奖培育项目 （）
