上海针灸杂志2017，Vol.36Issue(12)：1401-1405,5.DOI:10.13460/j.issn.1005-0957.2017.12.1401
合募配穴灸法治疗慢性萎缩性胃炎临床观察
Clinical Observation of Moxibustion at He-Sea and Front-Mu Points for Chronic Atrophic Gastritis
摘要
Abstract
Objective To observe the clinical efficacy of moxibustion at He-Sea plus Front-Mu points in treating chronic atrophic gastritis (CAG) due to deficient cold in spleen-stomach, and its effect on serum pepsinogen (PG) and gastrin. Method Sixty-three eligible patients with CAG due to deficient cold in spleen-stomach were divided into a control group (31 cases) and a treatment group (32 cases) by using random number table. The control group was intervened by Wei Fu Chun tablets, while the treatment group received moxibustion at He-Sea plus Front-Mu points, 12 weeks as a treatment course. Clinical efficacy, symptoms score of traditional Chinese medicine (TCM), serum PGⅠ, PG Ⅱ and gastrin levels were evaluated. Result The total effective rate was 93.8% in the treatment group, significantly better than that in the control group (P<0.05); the TCM symptoms scores dropped significantly in both groups after the treatment and in the follow-up study (P<0.01), and the treatment group was markedly superior to the control group (P<0.01); the levels of PG Ⅰ, PG Ⅰ/Ⅱ ratio (PGR) and gastrin-17 (G-17) increased significantly in the treatment group after the intervention (P<0.01), and PG Ⅱ dropped significantly (P<0.05); after the treatment, thelevels of PG I, PGR and G-17 increased significantly in the control group (P<0.05); after the intervention, the treatment group was significantly better than the control group in comparing the levels of PG Ⅰ, PGR and G-17 (P<0.01), and there was a significant difference in comparing the level of PG Ⅱ between the two groups after the intervention (P<0.05). The follow-up showed that the HP positive rate was 3.1% in the treatment group, significantly lower than that in the control group (P<0.05). Conclusion Moxibustion at He-Sea plus Front-Mu points can significantly improve CAG symptoms, enhance HT clearance and lower the relapse; its action mechanism is possibly through up-regulating PGⅠ, PGR and G-17 and down-regulating PG Ⅱ.关键词
温灸器灸/胃炎,萎缩性/配穴法/胃蛋白酶原/胃泌素类/穴,中脘/穴,足三里/灸法Key words
Instrument-based mild moxibustion/Gastritis/Atrophic/Points grouping method/Pepsinogen/Gastrin/Point/Zhongwan (CV12)/Point/Zusanli (ST36)/Moxibustion分类
医药卫生引用本文复制引用
张迪,袁星星,王炳予,张雅丽..合募配穴灸法治疗慢性萎缩性胃炎临床观察[J].上海针灸杂志,2017,36(12):1401-1405,5.基金项目
黑龙江省科技厅科技攻关项目(GC12C110) （GC12C110）
