实用妇产科杂志2017,Vol.33Issue(11):869-872,4.
不同方案GnRH-a降调节对轻中度子宫内膜异位症患者体外受精-胚胎移植结局的影响
Effect of Different Dosage forms of Gonadotrophin-Releasing Hormone Agonist on In-Vitro Fertilization-Embryo Transfer in Patients with Mild Endometriosis
王芳 1柯雪 1李敏1
作者信息
- 1. 成都市妇女儿童中心医院,四川成都610073
- 折叠
摘要
Abstract
Objective:To investigate the effect of different dosage forms of gonadotropin-releasing hormone agonist(GnRH-a) on in vitro fertilization-embryo transfer(IVF-ET) in patients with mild endometriosis.Methods:Totally 269 cycles(175 cases) of IVF-ET were included,which was divided into three groups:pro-long protocols (long acting 3.75 mg group,102 cycles),long protocols (long acting 1.875 mg group,87 cycles) and short protocols(short-acting 0.1 mg group,80 cycles).The clinical results were compared among groups.Results:The amount of gonadotropin(Gn) were significantly higher in pro-long protocol than the other ones.The implantation rate and clinical pregnancy rate were significantly higher in long acting 1.875mg group than the other two protocols (P < 0.05).Conclusions:Long protocol (long acting GnRH-a down-regulation,1o 875 mg) may be more beneficial to improve the implantation rate and clinical pregnancy rate of in vitro fertilization-embryo transfer(IVF-ET) in patients with endometriosis.关键词
促性腺激素释放激素激动剂/子宫内膜异位症/超长方案/长效长方案/短效长方案Key words
Gonadotropin-releasing hormone agonist/Endometriosis/Pro-long protocols/Long protocols/Short-acting protocols分类
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王芳,柯雪,李敏..不同方案GnRH-a降调节对轻中度子宫内膜异位症患者体外受精-胚胎移植结局的影响[J].实用妇产科杂志,2017,33(11):869-872,4.