实用肿瘤杂志2017,Vol.32Issue(6):547-550,4.
18F-FDG显像结合肿瘤标志物诊断肺癌的价值
Diagnostic value of 18 F-FDG metabolic imaging combined with serum tumor markers for lung cancer
何洁 1翟勇2
作者信息
- 1. 首都医科大学石景山教学医院,北京市石景山医院核医学科,北京100043
- 2. 首都医科大学宣武医院核医学科,北京100053
- 折叠
摘要
Abstract
Objective To assess the diagnostic value of 18F-fluoro-deoxyglucose (18 F-FDG) dual-headed coincidence imaging (DHCI) combined with serum tumor marker assays in the diagnosis of lung cancer.Methods Seventy-seven patients with pathologically proved lung cancer received 18 F-FDG DHCI examination and serum assays of CEA,CA 199,CA125 and CA153.Serum tumor marker assays were also conducted in 45 cases of benign lung diseases and 49 cases of healthy controls.Results There were significant differences in serum tumor marker levels among the lung cancer patients,lung benign disease patients and the controls (P < 0.05).The positive rate of 18 F-FDG DHCI in lung cancer was 85.7%,while the positive rates of CEA,CA125,CA153 and CA199 in lung cancer were 39.0%,24.7%,9.1% and 16.9%,respectively.The sensitivity of 4 tumor marker combined with DHCI was 92.2%.Conclusion The combination with serum tumor markers can increase the sensitivity of 18 F-FDG DHCI in diagnosis of lung cancer.关键词
肺肿瘤/诊断/18 F-FDG显像/生物学标记Key words
lung neoplasms/diagnosis/18 F-FDG metabolic imaging/biological markers分类
医药卫生引用本文复制引用
何洁,翟勇..18F-FDG显像结合肿瘤标志物诊断肺癌的价值[J].实用肿瘤杂志,2017,32(6):547-550,4.