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新鲜周期选择性单囊胚与双囊胚移植临床结局的比较

高红 王蔼明 林莉 孙金莉 颜晓红

生殖医学杂志2017,Vol.26Issue(12):1182-1186,5.
生殖医学杂志2017,Vol.26Issue(12):1182-1186,5.DOI:10.3969/j.issn.1004-3845.2017.12.004

新鲜周期选择性单囊胚与双囊胚移植临床结局的比较

Comparison of clinical outcomes between selective single blastocyst transfer and double blastocysts transfer in fresh embryo transfer cycles

高红 1王蔼明 2林莉 1孙金莉 1颜晓红1

作者信息

  • 1. 厦门大学附属第一医院生殖中心,厦门 361003
  • 2. 海军总医院,北京 100048
  • 折叠

摘要

Abstract

Objective:To compare the clinical outcomes of selective single blastocyst transfer(eSBT)with double blastocysts transfer(DBT)in fresh embryo transfer cycles among infertile women with normal ovarian reserve.Methods:A retrospective study including 210 women with normal ovarian reserve undergone fresh embryo transfer cycles,who were transferred at least one blastocyst in good quality,was conducted in our center from January 2014 to December 2015.The patients were categorized into two groups according to the number of blastocyst transferred as follows:eSBT group(n=127)and DBT group(n=83).The outcomes of pregnancy and newborn were compared between the two groups.Results:There were no significant differences in ovulation status,incidence of moderate or severe OHSS,embryo formation,clinical pregnancy rate,abortion rate,ectopic pregnancy rate,live birth rate,monozygotic twin rate and infant malformation rate between the two groups(P>0.05).The multiple birth rate(1.08% vs.49.21%),the late abortion rate(0% vs.7.94%),preterm birthrate(3.75% vs.20.37%),the rate of low birth-weight infants(6.17% vs.30.38%)in eSBT group were significantly lower than those of DBT group(P<0.05).However,the implanting rate(73.23% vs.61.45%)and the average neonatalweight [(3 160.06±441.94)g vs.(2 735.39±555.08)g] in eSBT group were significantly higher than those of DBT group(PΙ0.05).Conclusions:For patients under 40 years with normal ovarian reserve who had at least one goodquality blastocyst in fresh embryo transfer cycles,the selective single good quality blastocyst transfer should be given priority to consideration.

关键词

选择性单囊胚移植/双囊胚移植/多胎妊娠/妊娠结局

Key words

Selective single blastocyst transfer/Double blastocysts transfer/Multiple pregnancy/Pregnancy outcome

引用本文复制引用

高红,王蔼明,林莉,孙金莉,颜晓红..新鲜周期选择性单囊胚与双囊胚移植临床结局的比较[J].生殖医学杂志,2017,26(12):1182-1186,5.

生殖医学杂志

OACSTPCD

1004-3845

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