天然产物研究与开发2017，Vol.29Issue(11)：1858-1866,9.DOI:10.16333/j.1001-6880.2017.11.008
云南寻甸产臭参中化学成分研究
Compounds from Codonopsis pilosula Produced in Xundian of Yunnan Province
摘要
Abstract
Twenty four compounds were isolated from the roots of Codonopsis pilosula produced in Xundian of Yunnan province,which is well known as Choushen.Their structures were identified as choushenglycolipid A (1),(-)-(7R,8S,7'E)-4-hydroxy-3,5'-dimethoxy-7,4'-epoxy-8,3'-neolign-7'-ene-9,9'-diol 9'-ethyl ether (2),(7S,8R)-dihydrodehydrodiconiferyl alcohol (3),3-O-demethyldihydrodehydrodiconiferyl alcohol (4),prunustosanan AI (5),threo-guaiacylglycerol-β-O-4-lariciresinol ether (6),(+)-lariciresinol (7),5'-methoxylariciresinol (8),(-)-(7'S,8 S,8'R)-4,4'-dihydroxy-3,3',5,5'-tetramethoxy-7',9-epoxy-lignan-9'-ol-7-one (9),(7S,8S)-3-methoxy-3',7-epoxy-8,4'-oxyneoligna4,9-diol 9'-O-β-D-glucopyranoside (10),(-)-secoisolariciresinol (11),(+)-isolariciresinol (12),burselignan (13),threo-guaiacylglycerol-β-O-4'-coniferyl ether (14),4-[1-ethoxyl-1-(4-hydroxy-3-methoxy) benzyl] methyl-2-(4-hydroxy-3-methoxy) benzyl-3-hydroxymethyl-tetrahydro-furan (15),(-)-(7R,7'R,7" R,8 S,8'S,8" S)-4',4''-dihydroxy-3,3',3",5-tetramethoxy-7,9':7',9-diepoxy-4,8"-oxy-8,8'-sesquineolignan-7",9''-diol (16),(+)-pinoresinol-4'-O-β-D-glucopyranoside (17),retusin-8-methylether (18),ladanein (19),wighteone (erythrinin B) (20),3-methoxy-9-hydroxy-pterocarpan (21),trichocarpin (22),(Z)-8-O-β-D-glucopyranosylcinnamic acid (23) and 4-hydroxycinnamyl-O-β-D-glucopyranoside (24),respectively,by spectroscopic methods.Compound 1 is new and the other compounds with exception of compounds 7,11-13,23 and 24 were isolated from the genus Codonopsis for the first time.关键词
寻甸/臭参/木脂素/黄酮Key words
Xundian/Codonopsis pilosula/lignans/flavones分类
医药卫生引用本文复制引用
李小珍,晏永明,庄小翠,程永现..云南寻甸产臭参中化学成分研究[J].天然产物研究与开发,2017,29(11):1858-1866,9.基金项目
云南省生物科技重大项目(2014FC002) （2014FC002）
