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个体冲动性对物质滥用与成瘾的影响及脑机制

王志燕 崔彩莲

心理科学进展2017,Vol.25Issue(12):2063-2074,12.
心理科学进展2017,Vol.25Issue(12):2063-2074,12.DOI:10.3724/SP.J.1042.2017.02063

个体冲动性对物质滥用与成瘾的影响及脑机制

The effect and brain mechanism of individual impulsivity on drug abuse and addiction

王志燕 1崔彩莲1

作者信息

  • 1. 北京大学神经科学研究所/北京大学基础医学院神经生物学系,国家卫计委和教育部重点实验室, 北京 100191
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摘要

Abstract

Impulsivity is a multidimensional concept, which is generally defined as lack of foresight or consideration and judgment of actions. There is a double relationship between impulsivity and substance abuse, namely that trait impulsivity is an important risk factor for substance abuse and addiction, and the individual impulsivity could be damaged by abusing the addictive substances. The relationship between impulsivity and substance abuse, as well as its underlying neural mechanisms will be discussed in this review. Reorganization of previous research literatures on the trait-like impulsivity, or its alteration caused by substance abuse, and understanding of the neurobiological mechanisms implicated in this process, not only help us reveal the nature of occurrence, development and recurrence of substance abuse after abstinence, but also help us explore the behavioral intervention means other than drug therapies.

关键词

物质成瘾/抉择冲动性/运动冲动性

Key words

substance abuse and addiction/decisional impulsivity/motor impulsivity

分类

社会科学

引用本文复制引用

王志燕,崔彩莲..个体冲动性对物质滥用与成瘾的影响及脑机制[J].心理科学进展,2017,25(12):2063-2074,12.

基金项目

国家自然科学基金项目(81471353),国家重大科学研究计划(973计划)项目(2015CB553500)资助. (81471353)

心理科学进展

OA北大核心CHSSCDCSCDCSSCICSTPCD

1671-3710

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