新医学2017,Vol.48Issue(12):839-842,4.DOI:10.3969/j.issn.0253-9802.2017.12.004
微小RNA与脑缺血再灌注损伤发病机制的研究进展
Research progress on the relationship between microRNA and the pathogenesis of cerebral ischemia-reperfusion injury
杨莹 1王超云2
作者信息
- 1. 264003烟台,滨州医学院药学系
- 2. 葡萄酒学院
- 折叠
摘要
Abstract
Ischemia-reperfusion (I/R) injury is defined as the blood supply restored after a certain period of tissue ischemia.The physiological function is not recovered but more severe tissue dysfunction occurs,leading to more severe organ injury.At present,scholars have different opinions on the pathogenesis of I/R injury.Current prevention and treatment cannot yield satisfactory outcomes.Previous studies related to the pathogenesis of I/R injury obtain limited findings.The complex interaction among I/R injury-related signaling pathways seriously affects the understanding,prevention and treatment of I/R injury.Hence,the researchers have been exploring effective approaches to treat I/R injury.Recently,microRNA has been proven to contribute to the treatment of cerebral I/R injury.In this paper,the relationship between microRNA and the pathogenesis of cerebral I/R injury is briefly reviewed,aiming to provide reference to the researchers.关键词
脑缺血再灌注损伤/病理机制/微小RNAKey words
Cerebral ischemia/reperfusion injury/Pathogenesis/microRNA引用本文复制引用
杨莹,王超云..微小RNA与脑缺血再灌注损伤发病机制的研究进展[J].新医学,2017,48(12):839-842,4.