新医学2017，Vol.48Issue(12)：864-868,5.DOI:10.3969/j.issn.0253-9802.2017.12.009
维持性血液透析患者合并血管钙化情况的观察
Observation of maintenance hemodialysis patients complicated with vascular calcification
摘要
Abstract
Objective To investigate the risk factors of vascular calcification through analyzing the aorta status of the maintenance hemodialysis (MHD) patients.Methods In total,114 MHD patients received lateral plain X-ray of the abdomen.The score of abdominal aorta calcification (AAC) was calculated.According to the AAC score,all MHD patients were divided into the no or mild calcification group,and moderate or severe calcification group.The levels of total cholesterol,serum creatinine,serum iron,intact parathyroid hormone,blood glucose,blood calcium and blood phosphorous were quantitatively measured in two groups.The corrected calcium,dialysis vintage,age and gender composition were calculated.The risk factors of vascular calcification in MHD patients were analyzed by logistic regression analysis.The factors with P ＜ 0.10 analyzed by uni-variate logistic regression were included into multi-variate logistic regression analysis.Results Among 114 MHD patients,80 patients were assigned into the no or mild calcification group and 34 into the moderate or severe calcification group.Compared with the no or mild calcification group,the age of MHD patients was significantly older in the moderate or severe calcification group (P ＜ 0.05).Uni-variate logistic regression analysis revealed that the age,corrected calcium and blood glucose level were probably correlated with the incidence of vascular calcification (all P ＜ 0.10).Three parameters with statistical significance by uni-variate logistic regression,along with gender,product of calcium and phosphorus,PTH and dialysis vintage were included into the multi-variate logistic regression analysis.The statistical results demonstrated that the age,corrected calcium and product of calcium and phosphorus were positively correlated with the severity of vascular calcification (all P ＜ 0.05).Conclusions The age,corrected calcium and product of calcium and phosphorus of MHD patients are the risk factors of vascular calcification.Lowering the blood calcium level is probably a vital approach to mitigate the severity of vascular calcification in MHD patients.关键词
维持性血液透析/腹主动脉/血管钙化Key words
Maintenance hemodialysis/Abdominal aorta/Vascular calcification引用本文复制引用
刘红勇,张运强,李敏佳,李胜荣,廖学渊,廖志波,洪冬梅,吴勇林..维持性血液透析患者合并血管钙化情况的观察[J].新医学,2017,48(12):864-868,5.基金项目
梅州市科技项目(20158075) （20158075）
