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孔源性视网膜脱离患者术后视网膜微结构改变及其与视功能的相关关系

晏红改 李骏 聂红平 张世杰 杨柳

眼科新进展2017,Vol.37Issue(12):1135-1138,1142,5.
眼科新进展2017,Vol.37Issue(12):1135-1138,1142,5.DOI:10.13389/j.cnki.rao.2017.0286

孔源性视网膜脱离患者术后视网膜微结构改变及其与视功能的相关关系

Changes in retinal microstructure in patients with rhegmatogenous retinal detachment and its association with BCVA

晏红改 1李骏 1聂红平 1张世杰 1杨柳1

作者信息

  • 1. 100034北京市,北京大学第一医院视觉损伤与修复教育部重点实验室
  • 折叠

摘要

Abstract

Objective To observe the retinal microstructure changes in patients with rhegmatogenous retinal detachment following vitrectomy procedures and its correlation with the best corrected visual acuity (BCVA).Methods Patients who were diagnosed with rhegmatogenous retinal detachment and underwent vitrectomy were recruited in this study.BCVA and optical coherence tomography (OCT) examination were performed at 1 week,1 month,3 months and 6 months after operation for recording the neurosensory retinal thickness and outer nuclear layer thickness as well as observing the occurrence of ellipsoid zone,external limiting membrane rupture,macuiar edema,macular epiretinal membrane.Results A total of 32 eyes from 31 patients were followed up,and the BCVA became better as the follow-up prolonged.Both neurosensory retinal thickness and outer nuclear layer thickness thickened from 1 week [(122.75 ± 111.84) μm and (79.06 ±76.67) μm] to 3 months [(163.28 ± 133.10) μm and (108.66 ± 120.40)μm],and slightly thinned at 6 months [(159.50 ± 99.26) μm and (99.22 ± 74.89) μm].AS follow-up went by,the occurrence rate of ellipsoid zone and external limiting membrane rupture were 68.8% and 53.1%,65.6% and 46.9%,56.3% and 40.6%,50.0% and 37.5% at 1 week,1 month,3 months,6 months,respectively,and both variables were significantly correlation with the patients' BCVA.Conclusion The neurosensory retinal thickness and outer nuclear layer thickness in patients with rhegmatogenous retinal detachment became gradually thicker and the vision became better during follow-up.Meanwhile,the ellipsoid zone and external limiting membrane rupture are the key factors for patients' BCVA.

关键词

孔源性视网膜脱离/视网膜微结构/最佳矫正视力

Key words

rhegmatogenous retina[detachment/retinal microstructure/best corrected visual acuity

分类

医药卫生

引用本文复制引用

晏红改,李骏,聂红平,张世杰,杨柳..孔源性视网膜脱离患者术后视网膜微结构改变及其与视功能的相关关系[J].眼科新进展,2017,37(12):1135-1138,1142,5.

基金项目

国家自然科学基金资助项目(编号:81470650)National Natural Science Foundation of China (No:81470650) (编号:81470650)

眼科新进展

OA北大核心CSTPCD

1003-5141

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