中国医疗设备2017，Vol.32Issue(12)：7-10,39,5.DOI:10.3969/j.issn.1674-1633.2017.12.002
基于多模态神经影像的虚拟现实技术对三叉神经痛和面肌痉挛患者血管神经压迫的诊断价值
Value of Multimodal Image-Based Virtual Reality for the Diagnosis of Neurovascular Compression in Patients with Trigeminal Neuralgia and Hemi-Facial Spasm
摘要
Abstract
Objective To address the feasibility and predictive value of multimodal image-based virtual reality in preoperative evaluation of neurovascular compression in patients with trigeminal neuralgia and hemi-facial spasm. Methods This study included 40 patients who underwent microvascular decompression for classic primary trigeminal neuralgia or hemi-facial spasm. All patients underwent a preoperative 1.5 T MRI with plain and enhanced 3D T1-weighted magnetization prepared rapid acquisition gradient echo (MPRAGE) sequence, T2-weighted 3D sampling perfection with application-optimized contrasts by using different flip angle evolutions (3D-SPACE) sequence, and 3D time-of-flight (TOF) magnetic resonance angiography (MRA) sequence in combination. Multimodal MRI images were then co-registered with open-source software 3D Slicer, followed by three-dimensional image reconstruction to generate virtual reality images of possible neurovascular compression. Evaluation of neurovascular compression was then performed according to the virtual reality model and compared with the intra-operative findings. Results Preoperative MRI scan and virtual reality model reconstruction were successfully completed in all of the 40 cases. For predicting the existence of neurovascular compression, multimodal image-based virtual reality sensitivity was 97.4% (38/39), and specificity was 100%(1/1). The Kappa coefficient for predicting the offending vessel was 0.921 (95% confidence interval, 0.817~1.02), P=0.000<0.001. Conclusion Multimodal image-based virtual reality is proved to be reliable in detecting neurovascular compression and the offending vessel in patients with trigeminal neuralgia and hemi-facial spasm, which can provide some guide for the microvascular decompression surgery.关键词
三叉神经痛/面肌痉挛/血管神经压迫/虚拟现实技术/微血管减压术Key words
trigeminal neuralgia/hemi-facial spasm/neurovascular compression/virtual reality/microvascular decompression分类
生物科学引用本文复制引用
姚书敬,李昉晔,赵艺宁,张家墅,李翀,张治中,张军,陈晓雷..基于多模态神经影像的虚拟现实技术对三叉神经痛和面肌痉挛患者血管神经压迫的诊断价值[J].中国医疗设备,2017,32(12):7-10,39,5.基金项目
国家自然科学基金(81771481). （81771481）
