中国医疗设备2017，Vol.32Issue(12)：40-43,4.DOI:10.3969/j.issn.1674-1633.2017.12.009
单双弧设定对胸段食管癌容积旋转调强计划的剂量学比较
Dosimetric Comparison of Single-Arc and Double-Arc VMAT Plan for Treatment of Thoracic Esophageal Cancer
摘要
Abstract
Objective To explore the dosimetric characteristics of single arc and double arc volumetic modulation arc therapy (VMAT) for thoracic esophageal cancer. Methods Eleven thoracic esophageal cancer patients confirmed by pathology were reviewed and analyzed in the Monaco 5.11 treatment planning system (TPS). In this study, single arc VMAT (VMAT1) and double arc VMAT (VMAT2) plans were generated for each patient. The dose distribution to target and organs at risk (OAR), monitor units (MU) and delivery time were all recorded as dosimetric indices for plan comparison. Results The targets could meet the requirements of clinical prescription in two kinds of VMAT plans. The VMAT2 plan was superior to VMAT1 plan concerning target coverage and dose heterogeneity, and the difference had statistical significance (P<0.05). Compared with VMAT1 plan, the whole lung dose difference of V20 in VMAT2 plan had statistical significance (P<0.05), while the volume V5, V10,V30 of whole lung, V30,V40 of heart and the Dmax to spinal cord had no statistical significance (P<0.05). In terms of execution efficiency, the number of MUs in VMAT1 plan was significantly reduced and the delivery time was significantly shortened (P<0.05), comparing with VMAT2 plan. Conclusion Although the single-arc VMAT plan is worse than double-arc VMAT plan in terms of target coverage and dose heterogeneity, the treatment delivery time is significantly reduced and the implementation efficiency is highest. Therefore, it is recommended to choose single-arc VMAT plan for thoracic esophageal cancer.关键词
食管癌/容积旋转调强放疗/放疗弧数/剂量学Key words
esophageal cancer/volumetric modulated arc therapy/number of arc radiation/dosimetry.分类
医药卫生引用本文复制引用
王锐濠,张书旭,田允鸿,沈国辉,李万祯,廖博玉,王琳婧,李慧君..单双弧设定对胸段食管癌容积旋转调强计划的剂量学比较[J].中国医疗设备,2017,32(12):40-43,4.基金项目
国家自然青年科学基金项目(81502342) （81502342）
广东省科技计划项目(2016A02021517) （2016A02021517）
广州市卫生局医药卫生科技一般引导项目(20161A011083 （）
20161A011084 （）
20161A011085). （）
