中国医疗设备2017，Vol.32Issue(12)：87-90,4.DOI:10.3969/j.issn.1674-1633.2017.12.021
定量分析在不同超声造影特征甲状腺结节良恶性鉴别诊断中的价值
Value of Quantitative Analysis of Contrast-Enhanced Ultrasound in the Diagnosis of Thyroid Nodules with Different Enhancement Patterns
摘要
Abstract
Objective This study aims to investigate the value of quantitative analysis of contrast-enhanced ultrasound (CEUS) in the diagnosis of thyroid nodules under different enhancement patterns. Methods A total of 69 patients with 77 thyroid nodules undergoing CEUS were recruited. The quantitative parameters of nodules and the adjacent thyroid tissues such as peak intensity (PI), time to peak (TP), area under the curve (AUC) and mean transit time (MTT) were obtained. Two groups, hyper-enhancement group and hypo-enhancement group were established by the PI. Results Compared with hyper-enhancement group, the rate of malignant nodules was higher in hypo-enhancement group (65.7% in hypo-enhancement group VS. 29.4% in hyper-enhancement group, P=0.002). In the hypo-enhancement group, the rate of papillary carcinomas with the size less than 2.0 cm was significant higher than that in the hyper-enhancement group (80.8% in hypo-enhancement group VS. 36.4% in hyper-enhancement group, P=0.018). In the hypo-enhancement group, the AUC in benign nodules were significant higher than malignant nodules, no significant differences were noted in other parameters. In the hyper-enhancement group, there were no significant differences in all parameters between benign nodules and malignant nodules. Conclusion Hypo-enhancement is the common enhancement pattern of malignant thyroid nodules. The major enhancement mode of thyroid papillary carcinomas with the size more than 2.0 cm presents as hyper-enhancement. Quantitative analysis of hypo-enhancement thyroid nodules on CEUS is efficient in the differential diagnosis of thyroid nodules.关键词
甲状腺/乳头状癌/超声造影/定量分析/曲线下面积Key words
thyroid/papillary carcinomas/contrast-enhanced ultrasound/quantitative analysis/area under the curve (AUC)分类
医药卫生引用本文复制引用
李念芬,戚庭月,孙红光,封淏,诸林海,丁永玲..定量分析在不同超声造影特征甲状腺结节良恶性鉴别诊断中的价值[J].中国医疗设备,2017,32(12):87-90,4.基金项目
江苏省科技厅临床医学科技专项(BL2014064) （BL2014064）
扬州市科技计划社会发展面上项目(YZ2017085). （YZ2017085）
