针刺研究2017，Vol.42Issue(6)：502-506,5.DOI:10.13702/j.1000-0607.2017.06.006
针刺“神门”穴对睡眠剥夺大鼠脑电波及其认知能力的影响
Effects of Acupuncture at "Shenmen" (HT 7) on Brainwaves and Cognitive Ability in Rats with Sleep Deprivation
摘要
Abstract
Objective To observe the effects of acupuncture at "Shenmen" (HT 7) on brainwaves and cognitive ability in rats with sleep deprivation.Methods SD rats were randomly divided into control group,model group,acupuncture group and sham acupuncture group,15 rats in each group.Insomnia model rats were established by sleep deprivation for 72 hours.Acupuncture was applied to acupuncture group at bilateral "Shenmen" (HT 7) for 20 min,once daily for 7 days.Rats in the sham acupuncture group received superficial insertion of 1 mm and without retaining needle.The learning and memory abilities of rats were evaluated by Hexagonal maze.The BL-420 F physiological recorder was used to record EEG for 30 min on the 1st,4th,7th and 10th day respectively,and the frequency of each wave was analyzed.Results After sleep deprivation,the frequency of searching the exits of Hexagonal maze in the model group was obviously increased,the searching time was shortened,the number of search ing errors was increased obviously,and the cognitive rate was decreased (P＜0.01).Compared with the model group and thesham acupuncture group,the frequency of searching the exits in the acupuncture group was obviously decreased,the searching time was longer,the number of seeking errors was decreased,and the cognitive rate was increased (P＜0.05).Compared with the control group,the EEG of δ wave in the model group was decreased while β wave increased with statistical significance (P＜ 0.01).Compared with the model group,the δ wave of rats in the acupuncture group was significantly increased and the β wave was significantly decreased (P＜0.05).There were no statistically significant differences between the sham acupuncture group and the model group (P＞0.05).Conclusion Acupuncture at HT 7 can effectively improve the cognitive abilities and brainwaves in sleep deprived rats.关键词
针刺/神门穴/睡眠剥夺/认知能力/脑电波Key words
Acupuncture/Shenmen(HT 7)/Sleep deprivation/Cognitive ability/Brainwave分类
医药卫生引用本文复制引用
李佳,刘娇萍..针刺“神门”穴对睡眠剥夺大鼠脑电波及其认知能力的影响[J].针刺研究,2017,42(6):502-506,5.基金项目
国家自然科学基金(No.81403460) （No.81403460）
湖北中医药大学校级课题(No.2013-144,XJ 2014 KJ 003) （No.2013-144,XJ 2014 KJ 003）
