中国全科医学2017，Vol.20Issue(29)：3584-3589,6.DOI:10.3969/j.issn.1007-9572.2017.29.002
有氧运动和抗阻运动对糖调节受损患者空腹血糖及胰岛素抵抗的影响研究
Effects of Aerobic versus Resistance Exercise on Fasting Plasma Glucose and Insulin Resistance in Patients with Impaired Glucose Regulation
摘要
Abstract
Objective To study the effects of aerobic versus resistance exercise on fasting plasma glucose (FPG) and insulin resistance in patients with impaired glucose regulation (IGR) in order to provide an evidence for preventing and delaying the progression of diabetes mellitus.Methods From June to August 2015,143 IGR patients who were managed for a long time by Diecai,Nanmen and Xiufeng Community Health Service Center in Guilin were selected and divided into the control group (n =47),aerobic group (n =48),and resistance group (n =48) based on the random number table.Patients in the control group,aerobic group and resistance group were respectively treated with one follow-up every 3 months without other intervention measures,50-min moderate intensity aerobic exercise (rbythmic exercise,fit aerobics and so on),once every other day,50 -min moderate intensity resistance exercise (mainly training lumbar and abdominal muscles,leg and hip muscles,and upper limb muscles via using elastic rope to complete the assigned actions with 60％-70％ of one repetition maximum),once every other day,respectively.The FPG and fasting insulin (FINS) of the participants were measured before intervention,at the end of third,sixth and 12th months of intervention,respectively.The homeostatic model assessment of insulin resistance index (HOMA-IR) and insulin action index (IAI) were calculated.Results Thirty-eight patients in the control group,39 in the aerobic group and 38 in the resistance group completed the intervention.Intervention duration and mode exerted significant interaction on the FPG,FINS,HOMA-IR and IAI values (P ＜ 0.05),and they had obvious main effect on FPG,FINS,HOMA-IR and IAI values (P ＜ 0.05).When the third month of intervention ended,FPG values in the aerobic and resistance groups were lower than in the control group (P ＜ 0.05);FPG and HOMA-IR values decreased but IAI increased in both the aerobic and resistance groups compared with those before intervention (P ＜ 0.05).At the end of the sixth month of intervention,compared with the control group,both aerobic and resistance groups had lower FPG and FINS and HOMA-IR values but higher IAI (P ＜ 0.05);the resistance group had lower FPG values than aerobic group (P ＜ 0.05);FPG,FINS and HOMA-IR values declined while IAI increased in both the aerobic and resistance groups compared with those before intervention (P ＜ 0.05).At the conclusion of the 12th month of intervention,both aerobic and resistance groups had lower FPG and FINS and HOMA-IR values but higher IAI than the control group did (P ＜ 0.05);FPG values dropped in both the aerobic and resistance groups (P ＜ 0.05);FINS and HOMA-IR values lowered but IAI rose in all groups compared with those before intervention (P ＜ 0.05).Conclusion Both aerobic and resistance exercise produce similar effects on significantly improving the FPG and FINS levels and insulin resistance and sensitivity in patients with IGR.关键词
糖尿病前期/有氧运动/抗阻训练/血糖/胰岛素抗药性Key words
Prediabetic state/Aerobic exercise/Resistance training/Blood glucose/Insulin resistance分类
医药卫生引用本文复制引用
麻晓君,戴霞,陆丽荣,罗祖纯,韦春..有氧运动和抗阻运动对糖调节受损患者空腹血糖及胰岛素抵抗的影响研究[J].中国全科医学,2017,20(29):3584-3589,6.基金项目
广西医疗卫生适宜技术研究与开发课题项目(S201413-03) （S201413-03）
广西研究生教育创新计划项目(YCSZ2015111) （YCSZ2015111）
