中国全科医学2017，Vol.20Issue(30)：3740-3744,5.DOI:10.3969/j.issn.1007-9572.2017.00.065
主动脉夹层患者院内死亡危险因素分析
Risk Factors for Intrahospital Death of Aortic Dissection Patients
摘要
Abstract
Objective To explore the risk factors of intrahospital death in patients with aortic dissection (AD),in order to provide a reference for clinical effective treatment of the disease.Methods We collected the clinical data of 224 AD patients who received treatment in cardiac ICU,the First Affiliated Hospital of Xinjiang Medical University from January 2010 to January 2012 and met the inclusion criteria.According to the intrahospital outcome,they were divided into survival group (n =201) and death group (n =23).The clinical data (general data,basic signs and values of clinical markers) of patients were retrospectively analyzed.Risk factors of intrahospital death were analyzed.Results The differences in drinking history,hypertension history,onset time,DeBakey type and intrahospital surgical status between the two groups were revealed to be significant (P ＜ O.05).The levels of diastolic blood pressure,red blood cell count,hematocrit,percentage of eosinophil,percentage of basophil,eosinophil count,basophil count,hemoglobin,platelet count,thrombocytocrit,total protein,globulin,prothrombin time activity and fibrinogen in the death group appeared to be lower than those in the survival group (P ＜ 0.05).The death group had higher levels of fasting blood glucose and apolipoprotein AI,longer prothrombin time,higher international normalized ratio,and enlarged aortic sinus diameter compared with the survival group (P ＜ 0.05).The intrahospital death (dependent variable),and the independent variables of P ＜ 0.O1 filtered out by the single factor analysis,were analyzed by multiple Logistic regression analysis.The regression equation is Y =0.555-8.124 × basophil count-0.036 × value of hemoglobin + 0.104 × value of aortic sinus diameter.Conclusion Basophil count and value of hemoglobin are the protection factors of intrahospital death of patients with AD,while aortic sinus dimension is an independent risk factor.In view of this,these three markers should be monitored intensively.关键词
医院死亡率/主动脉夹层/危险因素Key words
Intrahospital mortality/Aortic dissection/Risk factors分类
医药卫生引用本文复制引用
张炜宗,马翔,王宝珠,汪浩..主动脉夹层患者院内死亡危险因素分析[J].中国全科医学,2017,20(30):3740-3744,5.基金项目
新疆维吾尔自治区杰出青年科技人才培养项目(2014711003) （2014711003）
