中国全科医学2017，Vol.20Issue(31)：3898-3901,4.DOI:10.3969/j.issn.1007-9572.2017.31.013
急性肺栓塞患者右心功能不全的相关预测指标研究
Predictors for Right Ventricular Dysfunction in Acute Pulmonary Embolism Patients
贾冬 1赵航 1张志刚 1赵敏1
作者信息
- 1. 10004辽宁省沈阳市,中国医科大学附属盛京医院
- 折叠
摘要
Abstract
Objective To investigate the predictors for right ventricular dysfunction (RVD) in acute pulmonary embolism (APE) patients.Methods We enrolled 127 patients who were diagnosed with APE in Shengjing Hospital of China Medical University from July 2013 to September 2016 and met the inclusion and exclusion criteria of this study.They were divided into RVD (+) group (n =51) and RVD (-) group (n =76) based on the results of echocardiography (ECHO).We collected and compared the demographic characteristics,values for heart rate (HR),D-dimer,red blood cell distribution width (RDW),N-terminal B-type natriuretic peptide (NT-pro-BNP) and cardiactroponin Ⅰ (cTnI) measured on admission between the groups.We conducted Logistic regression analyses to investigate the factors associated with RVD and implemented ROC curve analyses to assess the value of these factors for the prediction of RVD in APE.Results The prevalence of HR,D-dimer,cTnI and NT-pro-BNP abnormalities measured on admission differed significantly between the groups (P ＜ O.05),while the distribution of sex and age and value for RDW did not (P ＞ 0.05).Logistic regression analyses found that HR,cTnI and NT-pro-BNP were the associated factors for RVD in APE (P ＜0.05).ROC curve analyses demonstrated that,the average AUC for H R for the prediction of RVD in APE was 0.726 [95 ％ CI (0.673,0.815),P ＜ 0.001] with an optimal cut-off value of 89 beats/min,a sensitivity of 66.7％ and a specificity of 75.0％.Conclusion RVD is associated with HR,cTnI and NT-pro-BNP in APE patients.Therefore,APE patients should be highly suspected with RVD and given close monitoring when they are identified with HR ≥89 beats/min,cTnI and NT-pro-BNP abnormalities on admission.关键词
急性肺栓塞/右心功能不全/预测指标/心率Key words
Acute pulmonary embolism/Right ventricular dysfunction/Predictor/Heart rate分类
医药卫生引用本文复制引用
贾冬,赵航,张志刚,赵敏..急性肺栓塞患者右心功能不全的相关预测指标研究[J].中国全科医学,2017,20(31):3898-3901,4.
