中国全科医学2017，Vol.20Issue(33)：4178-4182,5.DOI:10.3969/j.issn.1007-9572.2017.00.141
基于正交试验设计的温和灸长强穴治疗肛门瘙痒症的最佳治疗方案研究
Determination ofthe Optimal Treatment Regimen for Pruritus Ani Using Mild Moxibustion at Changqiang Acupoint with Moxa Rolls Based on the Orthogonal Design
摘要
Abstract
Objective To determine the optimal treatment regimen for pruritus ani using mild moxibustion at Changqiang acupoint with moxa rolls based on the orthogonal design.Methods Thirty-two cases of pruritus ani received mild moxibustion at Changqiang acupoint and local perianal skin with moxa rolls in Anus & Intestine Surgery Outpatient,the First Affiliated Hospital of Zhejiang Chinese Medical University from 2013-2014 were enrolled.According to the self-developed orthogonal array,L423.Using 3 factors (A:duration of mild moxibustion per time,B:times of mild moxibustion,C:length of the mild moxibustion course) and 2-level collocation (elimination of the interaction efects between factors),they were randomly divided into group 1,group 2,group 3 and group 4.The therapeutic effects in all groups were assessed from the improvement achieved in pruritus severity score,itching frequency,and Dermatology Life Quality Index score.Results After treatment,the pruritus severity score,frequency of itching and Dermatology Life Quality Index score were all significantly improved in each of the groups (P ＜ 0.05 for each).The pruritus severity score and frequency of itching did not differ substantially between the groups after treatment (P ＜0.05 for each).After treatment,the Dermatology Life Quality Index score in group 1 was higher than that in group 3 (P ＜ 0.05),and that was lower in group 4 compared with group 1 and group 2 (P ＜ 0.05).The pruritus severity score was affected mostly by factor B,and it was equally affected by factors A and C.The optimal treatment regimen for pruritus using mild moxibustion at Changqiang acupoint and local perianal skin with moxa rolls was:the duration of treament per time:20 min;frequency of treament:twice a week;length of the course of treament:4 weeks.The frequency of itching was mostly affected by factor A,and it was equally affected by factors B and C.The optimal regimen for reducing the frequency of itching using mild moxibustion at Changqiang acupoint and local perianal skin with moxa rolls was:the duration of treament per time:20 min;frequency of treament:twice a week;length of the course of treament:2 weeks.All the three factors affected the Dermatology Life Quality Index score to different degrees,the order of them was A,B,C if sorted by the degree of influence from the the greatest to the smallest.The optimal regimen for improving the dermatology life quality using mild moxibustion at Changqiang acupoint and local perianal skin with moxa rolls was:the duration of treament per time:20 min;frequency of treament:twice a week;length of the course of treament:2 weeks.Conclusion For the treamentof pruritus ani,the effect of mild moxibustion at Changqiang acupoint is mostly associated with the duration of treament per time,and the ideal treamentregimen is as follows:the duration of treamentper time:20 min;frenqueny of treament:twice a week;length of the course of treament:2 weeks.关键词
肛门瘙痒症/艾条灸/正交试验Key words
Pruritus ani/Moxa stick moxibustion/Orthogonal test分类
医药卫生引用本文复制引用
徐利,卢汉体,葛琼翔,林国强..基于正交试验设计的温和灸长强穴治疗肛门瘙痒症的最佳治疗方案研究[J].中国全科医学,2017,20(33):4178-4182,5.基金项目
浙江省自然科学基金青年基金资助项目(Q15H270016) （Q15H270016）
