中国全科医学2017，Vol.20Issue(34)：4259-4264,6.DOI:10.3969/j.issn.1007-9572.2017.34.009
颈椎间盘退变与吸烟的关系研究
Correlation between Cervical Disc Degeneration and Smoking
摘要
Abstract
Objective To investigate the correlation between cigarette smoking and cervical disc degeneration. Methods We randomly selected 320 patients who visited Spine Surgery Outpatient,Shanghai East Hospital Affiliated to Tongji University with chief complaint of neck - shoulder pain during June 2014 to June 2016. According to the model of exposure to environmental tobacco smoke,they were divided into never - smoking group (n = 141),passive smoking group (n = 55),and active smoking group (n = 124). Each patient′s Miyazaki′s grading for cervical disc degeneration was analyzed based on their MRI films of the cervical spine. In addition,VAS score was applied to evaluate the degree of patients' neck -shoulder pain. With the help of statistical techniques,correlation between cigarette smoking and cervical disc degeneration was analyzed. Results Non - smokers had better Miyazaki grade for C2 / 3,C3 / 4,C5 / 6 segments and overall Miyazaki grade than passive smokers (P < 0. 05). Non - smokers presented better Miyazaki grade for C1 / 2 - C6 / 7 segments and overall Miyazaki grade than active smokers (P < 0. 05). The prevalence rate of Miyazaki grade Ⅳ and Ⅴ in C4 / 5 - C6 / 7 segments was higher than that in C1 / 2 - C3 / 4 segments in both active and passive smokers (P < 0. 05). The prevalence rate of Miyazaki grade Ⅳand Ⅴ in males was higher than that in females (P < 0. 05)in active smokers. Active smokers with 5 - 10 years of exposure to smoking demonstrated better Miyazaki grade compared with those with over 10 years (P < 0. 05). And a similar thing was observed in passive smokers (P < 0. 05). The VAS score differed significantly between the groups,in particular,smokers had much higher VAS score than non - smokers (P < 0. 05). Conclusion Smoking exacerbates cervical disc degeneration, especially the lower cervical disc degeneration. In addition,it increases the degree of neck - shoulder pain.关键词
椎间盘退行性变/颈椎病/吸烟/颈痛Key words
Intervertebral disc degeneration/Cervical spondylosis/Smoking/Neck pain分类
医药卫生引用本文复制引用
李浩曦,陈兆雄,黄宇峰,沈彬,雍之遥,吴德升..颈椎间盘退变与吸烟的关系研究[J].中国全科医学,2017,20(34):4259-4264,6.基金项目
国家自然科学基金资助项目(81371994) （81371994）
浦东新区卫生系统重点学科建设资助项目(PWZx2014-02) （PWZx2014-02）
上海市卫生计生委科研课题(201440016) （201440016）
