中国全科医学2017，Vol.20Issue(35)：4378-4382,5.DOI:10.3969/j.issn.1007-9572.2017.00.101
STOP-Bang问卷筛查重叠综合征的临床价值研究
Clinical Value of STOP-Bang Questionnaire in Screening Overlap Syndrome
摘要
Abstract
Objective To evaluate the clinical value of STOP-Bang questionnaire (SBQ)in screening overlap syndrome (OS). Methods The enrolled 320 participants were all from Department of Respiratory Medicine,Wuxi People′s Hospital. They were diagnosed as chronic obstructive pulmonary disease (COPD)and suspected with OS and received treatment between June 2015 and April 2017. All of them underwent polysomnography (PSG)and filled in the SBQ under the guidance of healthcare providers. Correlations of the values of main polysomnographic parameters for evaluating the severity of sleep disordered breathing and SBQ score were analyzed. Based on the value of apnea-hypopnea index (AHI),the patients were divided into three groups:5 ≤ AHI ≤15 group,15 < AHI ≤30 group and AHI > 30 group. We evaluated the sensitivity, specificity,positive and negative predictive values,draw ROC curve and calculated the areas under ROC curve (AUC)for SBQ score to predict OS. Results SBQ score had no significant linear correlation with age (r s = 0. 061,P = 0. 279),FEV 1 / FVC ratio (r s =-0. 910,P = 0. 102),and the value of mixed apnea index (r s = 0. 181,P = 0. 511). SBQ score was positively correlated with the value of BMI (r s = 0. 032,P < 0. 001),AHI (r s = 0. 538,P < 0. 001),hypopnea index (HI) (r= 0. 403,P < 0. 001),obstructive apnea index (OAI)(r s = 0. 526,P < 0. 001),central apnea index (CAI)(r s = 0. 265,P < 0. 001),and oxygen desaturation index (ODI)(r s = 0. 506,P < 0. 001),while it was negatively correlated with the value of FEV1 (r s =-0. 130,P = 0. 016). For the diagnosis of OS,the SBQ score displayed its sensitivity as 99. 2%,specificity as 85. 6%,positive predictive value as 80. 1% and negative predictive value as 99. 4% . The AUC of SBQ score for the prediction of OS in 5 ≤ AHI ≤15 group,15 < AHI ≤30 group and AHI > 30 group were 0. 915 (0. 737,0. 957),0. 861 (0. 812, 0. 910),0. 769 (0. 641,0. 895),respectively,and its optimal cutoff value for the prediction of OS in these three groups were 2,5,6,respectively. Conclusion In screening OS,SBQ score is correlated with the values of main parameters of PSG. It can be served as a good tool for screening and predicting OS,and is worthy of clinical application.关键词
睡眠呼吸暂停,阻塞性/肺疾病,慢性阻塞性/STOP-Bang问卷/筛查Key words
Sleep apnea,obstructive/Pulmonary disease,chronic obstructive/STOP-Bang questionnaire/Screening分类
医药卫生引用本文复制引用
郁震,卞涛,崔小川,陈志萍,支秀琴..STOP-Bang问卷筛查重叠综合征的临床价值研究[J].中国全科医学,2017,20(35):4378-4382,5.基金项目
江苏省无锡市卫计委科研项目(MS201507) （MS201507）
