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A抗原特异性自身抗体鉴定策略探讨1例

王丽 李学慧 冯智慧 张溪源

中国输血杂志2017,Vol.30Issue(10):1197-1199,3.
中国输血杂志2017,Vol.30Issue(10):1197-1199,3.DOI:10.13303/j.cjbt.issn.1004-549x.2017.10.034

A抗原特异性自身抗体鉴定策略探讨1例

One case of identification strategies of auto-anti-A

王丽 1李学慧 2冯智慧 3张溪源2

作者信息

  • 1. 威海市中心血站,山东威海264200
  • 2. 威海四0四医院
  • 3. 青岛市中心血站输血研究所
  • 折叠

摘要

Abstract

Objective To identify the cause for ABO typing discrepancy by auto-anti-A.Methods Tube method was applied in blood group serologic test.The exons 6 and 7 of ABO gene were analyzed by sequence analysis.Results Antigen A was identified on red blood cell and anti-A was detected in plasma.Auto-anti-A was determined by auto-absorption and elution.The sequence analysis identified the genotypes as A102/A102.Conclusion ABO blood group inconsistency was caused by auto-anti-A.The three-step analysis could be used to determine the cause of ABO inconsistency.

关键词

A抗原特异性自身抗体/ABO血型系统

Key words

auto-anti-A/ABO blood group

分类

医药卫生

引用本文复制引用

王丽,李学慧,冯智慧,张溪源..A抗原特异性自身抗体鉴定策略探讨1例[J].中国输血杂志,2017,30(10):1197-1199,3.

中国输血杂志

OACSTPCD

1004-549X

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