中国实验动物学报2017，Vol.25Issue(6)：637-642,6.DOI:10.3969/j.issn.1005-4847.2017.06.009
斑马鱼肠道微生物的研究进展
Research progress on intestinal tract microorganisms in zebrafish
摘要
Abstract
Intestinal microbiota as an important "microbial organ" in the human body may play a key role in the human development, intestinal barrier, immune regulation, digestion and nutrient absorption, detoxification, angiogenesis, as well as the occurrence and development of diseases. As a vertebrate biotype, zebrafish is widely used in the fields of de-velopmental biology, immunology, genetics, toxicology and the establishment of human disease models, because of their common development and phylogenetic system with humans. A number of unique features, including its transparent embry?os, rapid development, easy to take intestinal samples, and other advantages, made its wide popularity as an ideal model for the study of intestinal microbes. However, the research on zebrafish intestinal microbiology is still at an elementary stage. This paper summarizes the recent progress in research of zebrafish intestinal microbiota, including the related func?tion of intestinal microbes in zebrafish, the assembly and succession of intestinal microbial community and factors influen?cing the intestinal microbial structure, and provides a theoretical basis for studying the effects of intestinal microbes on hu?man health and its application in the treatment of diseases.关键词
肠道微生物/斑马鱼/相关功能/演替规律/影响因素/人类健康Key words
Intestinal microbiota/Zebrafish/Related function/Succession rule/Influencing factors/Human health分类
生物科学引用本文复制引用
张金花,桂芳,司婧,张红,周蓉,甘露..斑马鱼肠道微生物的研究进展[J].中国实验动物学报,2017,25(6):637-642,6.基金项目
国家自然科学基金联合基金重点项目(No.U1432248) （No.U1432248）
科技部国家重点研发项目(No.2016YFC0904600) （No.2016YFC0904600）
国家自然科学基金青年科学基金(No.11605255) （No.11605255）
兰州市科技计划项目(2015-3?75). （2015-3?75）
