新生儿坏死性小肠结肠炎动物模型研究进展OA北大核心CSCDCSTPCD
Progress in research on animal models of neonatal necrotizing enterocolitis
新生儿坏死性小肠结肠炎(NEC)是新生儿时期严重的胃肠道疾病,病死率高,多见于早产儿,极低出生体重儿,但确切病因及发病机制尚未阐明.积极探寻其发病机制,需建立可靠的动物模型以助于对该病的病因、发病机制及防治等各方面进行深入研究,以改善NEC患儿预后有重要意义.
Neonatal necrotizing enterocolitis ( NEC) is a severe gastrointestinal disease with high mortality. Stud-ies have suggested that NEC are associated with prematurity and very?low birth weight, but the exact etiology and pathogen?esis has not been elucidated. Therefore, it is important to build an ideal NEC model to explore the pathogenesis and pre?vention measures of NEC to reduce the incidence and severity of NEC.
杨凯蒂;贺雨;曾本华;肖洒;艾青;魏泓;余加林
重庆医科大学附属儿童医院新生儿中心,重庆 400014儿童发育疾病研究教育部重点实验室,重庆 400014儿童发育重大疾病国家国际科技合作基地,重庆 400014儿科学重庆重点实验室,重庆 410014重庆医科大学附属儿童医院新生儿中心,重庆 400014儿童发育疾病研究教育部重点实验室,重庆 400014儿童发育重大疾病国家国际科技合作基地,重庆 400014
生物科学
坏死性小肠结肠炎动物模型新生儿
Neonatal necrotizing enterocolitisAnimal model
《中国实验动物学报》 2017 (6)
689-692,4
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